geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Linking SIRT2 to Parkinson's disease


, : Linking SIRT2 to Parkinson's disease. Acs Chemical Biology 2(8): 529-532

A recent study has identified selective inhibitors of the human silent information regulator 2 NAD(+)-dependent protein deacetylase, SIRT2, and has shown that these compounds protect against alpha-synuctein-mediated toxicity in cellular models of Parkinson's disease. The inhibitors were found to ameliorate dopaminergic cell death in vitro and in a Drosophila model of Parkinson's disease.

US$19.90

PMID: 17708669

DOI: 10.1021/cb700160d


Other references

Cajkovac, S., 1964: Clinical pictures of our Candida mycoses. Of 1, 988 strs. of C. albicans isolated, 1, 193 came from women and 795 from men. Most (870) were isolated from the interdigital spaces of the hands and feet, secondly from nail folds.

Clarke, J.M.; Deegan, T.; McKendrick, C.S., 1968: Blood volume changes afger myocardial infarct. British Heart Journal 30(6): 870-870

Whitridge, J., 1959: Nurse-midwife fills a gap in obstetric care. Modern Hospital 93: 95-98

Cita Maria Bianca, 1982: The Messinian salinity crisis in the Mediterranean; a review. Geodynamics Series: ges 113-140. 1982.

Rosenthal, R.; Conen, D., 2000: Pheochromocytoma: diagnosis and treatment. Phaeochromocytoma is a rare tumour which produces a variety of symptoms. The most important factor is to think of the diagnosis, and there are many biochemical and pharmacological tests as well as radiological procedures to confirm it. Once the ph...

Kukresh, Np, 1979: Effects of nitrogen fertilizer applied at different times on the grain yield and protein content of winter crops. Agrokhimiia (4) 14-20

Talib, A.; Faisal, S.M.S., 2007: On the occurrence of microfossils (Foraminiferida) in the Jurassic rocks of Ler Dome, Kutch Mainland, Gujarat. Current Science (Bangalore) 92(5): 595-596

Treffert, D.A., 1979: "Wellness"......in perspective. Wisconsin Medical Journal 78(9): 3-4

Paksoy, M.; Akll, M., 1994: The effects of different prunings on the yield and quality of eggplant cultivars grown in greenhouse conditions. Plants of the F1 aubergine cultivars Dusky, Vittoria, Valentina, Indra, Sicilia, Palmira and Imperial were pruned to leave either 2 or 3 main shoots above 30-35 cm height, with lateral shoots pruned to leave a fruit and 3 leaves or left not pruned...

Hammen, T.Van-Der, 1974: The Pleistocene changes of vegetation and climate in tropical South America. Journal of biogeography: 1 (1) 3-26