+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Long-term effects of feeding monensin on milk fatty acid composition in lactating dairy cows

, : Long-term effects of feeding monensin on milk fatty acid composition in lactating dairy cows. Journal of Dairy Science 90(11): 5126-5133

The objective of this study was to determine the long-term effects of feeding monensin on milk fatty acid (FA) profile in lactating dairy cows. Twenty-four lactating Holstein dairy cows (1.46 +/- 0.17 parity; 620 +/- 5.9 kg of live weight; 92.5 +/- 2.62 d in milk) housed in a tie-stall facility were used in the study. The study was conducted as paired comparisons in a completely randomized block design with repeated measurements in a color-coded, double blind experiment. The cows were paired by parity and days in milk and allocated to 1 of 2 treatments: 1) the regular milking cow total mixed ration (TMR) with a forage-to-concentrate ratio of 60:40 (control TMR; placebo premix) vs. a medicated TMR [monensin TMR; regular TMR + 24 mg of Rumensin Premix per kg of dry matter (DM)] fed ad libitum. The animals were fed and milked twice daily (feeding at 0830 and 1300 h; milking at 0500 and 1500 h). Milk samples were collected before the introduction of treatments and monthly thereafter for 6 mo and analyzed for FA composition. Monensin reduced the percentage of the short-and medium-chain saturated FA 7:0, 9:0, 15:0, and 16:0 in milk fat by 26, 35, 19, and 6%, respectively, compared with the control group. Monensin increased the percentage of the long-chain saturated FA in milk fat by 9%, total monounsaturated FA by 5%, total n-6 polyunsaturated FA (PUFA) by 19%, total n-3 PUFA by 16%, total cis-18:1 by 7%, and total conjugated linoleic acid (CLA) by 43% compared with the control group. Monensin increased the percentage of docosahexaenoic acid (22:6n-3), docosapentaenoic acid (22:5n-3), and cis-9, trans-11 CLA in milk fat by 19, 13, and 43%, respectively, compared with the control. These results suggest that monensin was at least partly effective in inhibiting the biohydrogenation of unsaturated FA in the rumen and consequently increased the percentage of n-6 and n-3 PUFA and CLA in milk, thus enhancing the nutritional properties of milk with regard to human health.


PMID: 17954753

DOI: 10.3168/jds.2007-0242

Other references

Zhao, J-ling.; Zhao, J.; Jiao, H-jun., 2014: Synergistic growth-suppressive effects of quercetin and cisplatin on HepG2 human hepatocellular carcinoma cells. Quercetin, a natural flavonoid, exhibits anticancer effects. The aim of this study is to determine whether the combination of quercetin with cisplatin, a conventional chemotherapeutic drug, would have synergistic suppressive effects on hepatocellu...

Ward, J.D., 1969: Gram-negative septicaemia during haemorrhage from an anastomotic ulcer. Gram-negative septicaemia (Klebsiella) occurred on two occasions in a patient bleeding from an anastomotic ulcer. It is postulated that the presence of this organism in the gut of such a patient provided the portal of entry for this infection.

Burkhardt, F.; Porter, D.M.; Harvey, J.; Topham, J.R., 1997: The correspondence of Charles Darwin. Volume 10 1862. Unknown

Kitahara, F.; Shimazaki, R.; Sato, T.; Kojima, Y.; Morozumi, A.; Fujino, M.A., 2002: Severe atrophic gastritis with Helicobacter pylori infection and gastric cancer. BACKGROUND: We conducted a case-control study to evaluate whether patients with severe gastric atrophy (indicated by serum pepsinogen concentration) have a high risk of gastric cancer.METHODS: At the time of diagnosis of gastric cancer, sera from...

Palcoux, J.B.; Niaudet, P.; Goumy, P., 1994: Side effects of levamisole in children with nephrosis. Pediatric Nephrology 8(2): 263-264

Hirashima, Y., 1977: Revision of the japanese species of nesoprosopis new record with descriptions of 2 new species hymenoptera colletidae hylaeus. Nesoprosopis, a subgenus of Hylaeus that is famous for its adaptive radiation in the Hawaiian Islands [USA], is reported from Japan for the 1st time. Seven species of Nesoprosopis are recognized there and they are divided into 2 species-groups and...

Fauchier, L.; Babuty, D.; Melin, A.; Bonnet, P.; Cosnay, P.; Paul Fauchier, J., 2004: Heart rate variability in severe right or left heart failure: the role of pulmonary hypertension and resistances. The decrease in heart rate variability (HRV) might be related to the hemodynamic status in heart failure. However, HRV in patients with severe isolated right heart failure has not been extensively studied. This study compared HRV in patients with...

Brehme, S.; Thiede, W.; Borges, E., 2006: Beitraege zur Vogelwelt Libyens, VIII: Laniidae bis Emberizidae. Information on the appearance of 49 species in areas of Tripolitania and the Fezzan is provided for the periods 6 Nov. 1969-31 Dec. 1971 and 9 Oct. 1996-21 Oct. 1996 in continuation by BREHME & THIEDE (2001) and BREHME, THIEDE & BORGES (2002 a, b,...

Naumovski, L.; Cleary, M.L., 1994: Bcl2 inhibits apoptosis associated with terminal differentiation of HL-60 myeloid leukemia cells. The Bcl2 protein inhibits apoptosis (programmed cell death) induced by a variety of noxious stimuli. However, relatively little is known about its effect on apoptosis that occurs after terminal differentiation. Bcl2 protein levels decrease during...

Motta, G.; Guerrieri, S.; Malagù, I., 1966: Organ hypothermia. Changes in cardiac activity in the course of deep gastric local hypothermia. (Clinical research). Minerva Medica 57(88): 3674-3677