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Special issues in the management of young children, older adults, and the developmentally disabled


, : Special issues in the management of young children, older adults, and the developmentally disabled. Journal of Child Neurology 22(5 Suppl): 53s-60s

The very young, the very old, and those with developmental disability have an increased risk of both epilepsy and prolonged and repetitive seizures. The special issues that affect their management are reviewed. Polypharmacy that occurs because of comorbid illnesses requiring chronic medication can result in dangerous drug-drug interactions. The antiepileptic drug's pharmacokinetic profile must be factored when treating young children and older adults. Patients who have taken an older enzyme-inducing antiepileptic drug for years may have a markedly induced hepatic enzyme system that may alter drug metabolism. Overdose or toxicity may occur in older adults who may metabolize and clear antiepileptic drugs more slowly than younger patients. Benzodiazepines are the most rapidly effective acute therapy for repetitive or prolonged seizures. It is important to have a plan for management of prolonged and repetitive seizures. Long-term therapy should be managed in a manner that will eliminate the need for rescue therapies and visits to the emergency department.

US$19.90

PMID: 17690088

DOI: 10.1177/0883073807303253


Other references

Nagano, N.; Tabata, H.; Hashimoto, K., 1991: Anticoagulant-related intracerebral hemorrhage in patients with prosthetic heart valves--report of two cases. Two cases of intracerebral hemorrhage in patients with prosthetic heart valves receiving anticoagulant therapy without preceding embolic cerebral infarction are reported. Phytonadione and fresh frozen plasma were immediately given, and the intrace...

Sede, M.M.; Moretti, F.A.; Laufer, N.L.; Jones, L.R.; Quarleri, J.F., 2015: HIV-1 tropism dynamics and phylogenetic analysis from longitudinal ultra-deep sequencing data of CCR5- and CXCR4-using variants. Coreceptor switch from CCR5 to CXCR4 is associated with HIV disease progression. The molecular and evolutionary mechanisms underlying the CCR5 to CXCR4 switch are the focus of intense recent research. We studied the HIV-1 tropism dynamics in relat...

Petit, C.; Conan, J-Marc.; Kulcsár, C.; Raynaud, H-Francois.; Fusco, T., 2008: First laboratory validation of vibration filtering with LQG control law for adaptive optics. We present a first experimental validation of vibration filtering with a Linear Quadratic Gaussian (LQG) control law in Adaptive Optics (AO). A quasi-pure mechanical vibration is generated on a classic AO bench and filtered by the control law, lea...

Coelho, JAP. da Graca Lopes, R.; Rodrigues, ES.; Puzzi, A., 1985: Relacao peso-comprimento e tamanho de inicio de primeira maturacao gonadal para o Sciaenidae Stellifer rastrifer (Jordan, 1889), no litoral do estado de Sao Paulo. Boletim do Instituto de Pesca (Sao Paulo): 122: 99-107

Kim, Y.R.; Kihara, J.E., 1999: Hematology reference control and method of preparation. Official Gazette of the United States Patent & Trademark Office Patents 1218(2): 1276-1277, Jan 12

Chopin, T.; Gallant, T.; Davison, I., 1995: Phosphorus and nitrogen nutrition in Chondrus crispus (Rhodophyta): Effects on total phosphorus and nitrogen content, carrageenan production, and photosynthetic pigments and metabolism. The existence of a phenomenon in phosphorus (P) nutrition comparable to the "Neish effect" in nitrogen (N) nutrition (an inverse relation between seawater N enrichment and carrageenan content) was investigated in the temperate red alga C...

Montagnani, C.; Prato, M.; Scolfaro, C.; Colombo, S.; Esposito, S.; Tagliabue, C.; L.V.cchio, A.; Bruzzese, E.; Loy, A.; Cursi, L.; Vuerich, M.; de Martino, M.; Galli, L., 2016: Carbapenem-resistant Enterobacteriaceae Infections in Children: An Italian Retrospective Multicenter Study. The spread of carbapenem-resistant Enterobacteriaceae (CRE) is a health problem of major concern. CRE-related infections have significant morbidity and mortality, but data on CRE infection in pediatric population are limited. The aim of this study...

Inoue, S.; Yamanaka, T.; Okamoto, H.; Hosoi, H., 2004: Effect of a glutamate blocker, ipenoxazone hydrochloride on the hypoxia-induced firing in the medial vestibular nucleus. To elucidate the effectiveness of the drug in the treatment of vertebrobasilar insufficiency (VBI), we performed an electrophysiological study to examine the effects of ipenoxazone hydrochloride, a glutamate blocker, on hypoxia-induced firing in t...

Moreno, A.D.; Ibarra, D.; Fernández, Jé.L.; Ballesteros, M., 2012: Different laccase detoxification strategies for ethanol production from lignocellulosic biomass by the thermotolerant yeast Kluyveromyces marxianus CECT 10875. In this work, laccase enzymes were evaluated to detoxify the whole slurry from steam-exploded wheat straw. For it, two different strategies, laccase treatment before or after enzymatic hydrolysis, were employed. The detoxification efficiency was a...

Xu, H.; Wang, Y.; Qiu, G.; Ye, Q.; Zhang, J., 2002: Surgical treatment of spinal myeloma, report of 19 cases. To discuss the indications for surgical procedures of spinal myeloma. A retrospective analysis was made of the data of operation results of Nineteen patients with spinal myeloma, 13 males and 6 females, with the mean age of 45.1 (range 31 approxim...