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The pineal gland: a supplemental source of hypothalamic-releasing hormones

, : The pineal gland: a supplemental source of hypothalamic-releasing hormones. Endocrinology 94(5): 1422-1426

Human foetal small and large intestine responded to prostaglandins E(2) and F(2alpha), the gestational age of the tissue being between 14 and 26 weeks. The predominant response to both prostaglandins was a contraction of each region of the intestine studied.


PMID: 4207300

DOI: 10.1210/endo-94-5-1422

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Lin, C-Po.; Ban, Y.; Lyu, Y.Lisa.; Liu, L.F., 2009: Proteasome-dependent processing of topoisomerase I-DNA adducts into DNA double strand breaks at arrested replication forks. Reversible topoisomerase I (Top1)-DNA cleavage complexes are the key DNA lesion induced by anticancer camptothecins (CPTs) (e.g. topotecan and irinotecan) as well as structurally perturbed DNAs (e.g. oxidatively damaged, UV-irradiated, or alkylate...

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