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Geography & Life Sciences: Chapter 18020

Chapter 18020 provides bibliographic information on scholary research in geography and in the life sciences.



Mutagenesis of ligands to the (4Fe-4S) center of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase. The Journal of Biological Chemistry 261: 416-23

Mutagenesis of p38a MAP Kinase Establishes Key Roles of Phe169 in Function and Structural Dynamics and Reveals a Novel DFG-OUT State. Biochemistry (American Chemical Society) 46(19): 87-96

Mutagenesis of residues flanking Lys-40 enhances the enzymatic activity and reduces the angiogenic potency of angiogenin. Biochemistry 29(31): 7297-7302

Mutagenesis of retroviral vectors transducing human b-globin gene and b-globin locus control region derivatives results in stable transmission of an active transcriptional structure. The EMBO Journal 13: 65-76

Mutagenesis of subunit d from Escherichia coli F1F0-ATP synthase. The Journal of Biological Chemistry 269: 8-26

Mutagenesis of the C2 domain of protein kinase C-a. Differential roles of Ca2+ ligands and membrane binding residues. The Journal of Biological Chemistry 273(28): 544-52

Mutagenesis of the N- and C-terminal cysteine pairs of Tn501 mercuric ion reductase: consequences for bacterial detoxification of mercurials. Biochemistry 28(3): 1183-1194

Mutagenesis of the Runt Domain Defines Two Energetic Hot Spots for Heterodimerization with the Core Binding Factor b Subunit. The Journal of Biological Chemistry 278(35): 097-104

Mutagenesis of the a subunit of the F1F0-ATPase from Escherichia coli. Mutations at Glu-196, Pro-190, and Ser-199. The Journal of Biological Chemistry 263: 99-605

Mutagenesis of the amino terminus of the a subunit of the G protein Go. In vitro characterization of aobc interactions. The Journal of Biological Chemistry 267: 72-7

Mutagenesis of the amino-terminal glycine to alanine in Gs a subunit alters bc-dependent properties and decreases adenylylcyclase activation. The Journal of Biological Chemistry 268: 6-41

Mutagenesis of the c-Carboxyglutamic Acid Domain of Human Factor VII to Generate Maximum Enhancement of the Membrane Contact Site. The Journal of Biological Chemistry 278(10): 63-9

Mutagenesis of the central hydrophobic cluster in Ab42 Alzheimer's peptide. Side-chain properties correlate with aggregation propensities. The FEBS Journal 273(3): 8-68

Mutagenesis of the conserved aspartic acid 443, glutamic acid 478, asparagine 494, and aspartic acid 498 residues in the ribonuclease H domain of p66/p51 human immunodeficiency virus type I reverse transcriptase. Expression and biochemical analysis. Journal of Biological Chemistry 269(30): 19245-9

Mutagenesis of the conserved residue Glu259 of Gsa demonstrates the importance of interactions between switches 2 and 3 for activation. The Journal of Biological Chemistry 274(8): 77-84

Mutagenesis of the ligand binding domain of the human retinoic acid receptor a identifies critical residues for 9-cis-retinoic acid binding. The Journal of Biological Chemistry 270: 258-63

Mutagenesis of the regulatory domain of rat protein kinase C-h. A molecular basis for restricted histone kinase activity. The Journal of Biological Chemistry 268: 498-504

Mutagenesis of the regulatory subunit (RIIb) of cAMP-dependent protein kinase IIb reveals hydrophobic amino acids that are essential for RIIb dimerization and/or anchoring RIIb to the cytoskeleton. The Journal of Biological Chemistry 270: 35-44

Mutagenesis of the regulatory subunit of yeast cAMP-dependent protein kinase. Isolation of site-directed mutants with altered binding affinity for catalytic subunit. Journal of Biological Chemistry 263(19): 9149-9154

Mutagenesis within human FceRIa differentially affects human and murine IgE binding. Journal of Immunology 168(4): 87-95

Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America 101(39): 14051-6

Mutagenic activity of incense smoke in Salmonella typhimurium. Bulletin of Environmental Contamination and Toxicology 38(5): 827-833

Mutagenic activity of the liquid waste from the production of acetonitrile. Bulletin of Environmental Contamination and Toxicology 32(6): 742-748

Mutagenic analysis of double-stranded RNA adenosine deaminase, a candidate enzyme for RNA editing of glutamate-gated ion channel transcripts. Journal of Biological Chemistry 270(29): 17098-17105

Mutagenic and nonmutagenic bypass of DNA lesions by Drosophila DNA polymerases dpolh and dpoli. The Journal of Biological Chemistry 276(18): 155-63

Mutagenic and thermodynamic analyses of residual structure in the a subunit of tryptophan synthase. Biochemistry (American Chemical Society) 35: 88-94

Mutagenic effect of a pesticide (Ekatin) in the soybean test system. Environmental and Experimental Botany 23: 101

Mutagenic potential of sediments from the Grand Calumet River. Bulletin of Environmental Contamination and Toxicology 47(2): 308-315

Mutagenic properties of pirimiphos-methyl in male mice. Bulletin of Environmental Contamination and Toxicology 36(5): 680-684

Mutagenic specificity of a novel T4 DNA polymerase mutant. Genetics 106(3): 335-345

Mutagenicity assays of leachate from domestic waste landfills in Japan: the establishment of a protocol for measuring mutagenicity levels of leachate. Bulletin of Environmental Contamination and Toxicology 46(4): 561-568

Mutagenicity of Tama River sediments. Bulletin of Environmental Contamination and Toxicology 39(4): 696-700

Mutagenicity of air pollutants collected at industrial, urban-residential and rural areas. Bulletin of Environmental Contamination and Toxicology 32(6): 688-692

Mutagenicity of drinking well water. Bulletin of Environmental Contamination and Toxicology 51(4): 545-550

Mutagenicity of heavy metals. Bulletin of Environmental Contamination and Toxicology 40(4): 597-603

Mutagenicity of materials extracted from synthetic rubber. Agricultural and Biological Chemistry 50: 3-14

Mutagenicity of nitrohumic acid in Salmonella typhimurium strains. Bulletin of Environmental Contamination and Toxicology 39(5): 843-847

Mutagenicity of pyrolyzates of natural substances toward Salmonella typhimurium TA97. Agricultural and Biological Chemistry 49: 93-5

Mutagenicity of the sunlight-exposed sample of pyrene in Salmonella typhimurium TA98. Bulletin of Environmental Contamination and Toxicology 33(4): 410-417

Mutagenicity of volatile q-alkenyl isothiocyanates and their corresponding cyanoepithioalkanes. Bioscience, Biotechnology, and Biochemistry 56: 9-60

Mutagenicity studies of size-fractionated oil fly ash in the Ames Salmonella typhimurium assay. Bulletin of Environmental Contamination and Toxicology 32(2): 179-186

Mutagenicity, acute toxicity, and bioaccumulation potential of six chlorinated styrenes. Bulletin of Environmental Contamination and Toxicology 35(4): 525-530

Mutagenicity, new horizons in genetic toxicology (book review). BioScience 34: 6

Mutant analysis reveals a specific requirement for protein P30 in Mycoplasma pneumoniae gliding motility. Journal of Bacteriology 187(18): 6281-6289

Mutant GABAA receptor c2-subunit in childhood absence epilepsy and febrile seizures. Nature Genetics 28(1): 52

Mutant NDUFV1 subunit of mitochondrial complex I causes leukodystrophy and myoclonic epilepsy. Nature Genetics 21(3): 260-261

Mutant POLG2 Disrupts DNA Polymerase g Subunits and Causes Progressive External Ophthalmoplegia. American Journal of Human Genetics 78(6): 26-34

Mutant U2 snRNAs of Xenopus which can form an altered higher order RNA structure are unable to enter the nucleus. Experimental Cell Research 172(2): 329-339

Mutant U5A cells are complemented by an interferon-ab receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster. The EMBO Journal 14: 00-8

Mutant a-Latrotoxin (LTXN4C) Does Not Form Pores and Causes Secretion by Receptor Stimulation. This Action Does Not Require Neurexins. The Journal of Biological Chemistry 278(33): 058-66

Mutant aminoacyl-tRNA synthetase that compensates for a mutation in the major identity determinant of its tRNA. Biochemistry 30(10): 2635-2641

Mutant and wild type human a-synucleins assemble into elongated filaments with distinct morphologies in vitro. The Journal of Biological Chemistry 274(12): 2

Mutant b-spectrin 4 causes auditory and motor neuropathies in quivering mice. Nature Genetics 29(1): 5

Mutant farnesyltransferase b subunit of Saccharomyces cerevisiae that can substitute for geranylgeranyltransferase type I b subunit. Proceedings of the National Academy of Sciences of the United States of America 92: 04-8

Mutant genes in familial Alzheimer's disease and transgenic models. Annual Review of Neuroscience 21: 479-505

Mutant glycosyltransferase and altered glycosylation of a-dystroglycan in the myodystrophy mouse. Nature Genetics 28(2): 1-154

Mutant isolation and gene transfer as tools in study of transport proteins. American Journal of Physiology 252(5 Pt 1): C457-C467

Mutant l repressors with increased operator affinities reveal new, specific protein-DNA contacts. Genetics 130: 26

Mutant membrane protein toxicity. Journal of Biological Chemistry 273(43): 28078-28084

Mutant mice mimic human sickle cell anemia. Science 278: 3-4

Mutant mouse lysozyme carrying a minimal T cell epitope of hen egg lysozyme evokes high autoantibody response. Journal of Immunology 165(7): 3606-3611

Mutant myosin VIIa causes defective melanosome distribution in the RPE shaker-1 mice. Nature Genetics ): 7-18

Mutant offspring. Five new Forsythia cultivars are the progeny of one irradiated Forsythia (times) intermedia 'Lynwood Gold'. American Nurseryman 167: 7-32

Mutant p53 Attenuates the SMAD-Dependent Transforming Growth Factor b1 (TGF-b1) Signaling Pathway by Repressing the Expression of TGF-b Receptor Type II. Molecular and Cellular Biology 27(23): 28-42

Mutant presenilin 2 transgenic mice. A large increase in the levels of Ab42 is presumably associated with the low density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin. The Journal of Biological Chemistry 275(36): 901-8

Mutant prohead RNAs in the in vitro packaging of bacteriophage f29 DNA-gp3. Journal of Molecular Biology 223: 1-8

Mutant s factor blocks transition between promoter binding and initiation of transcription. Proceedings of the National Academy of Sciences of the United States of America 89: 58-62

Mutants and Intersexual Heterokaryons of Blakeslea trispora for Production of b-Carotene and Lycopene. Applied and Environmental Microbiology 69(7): 43-8

Mutants at xantha and albina loci in relation to chloroplast biogenesis in barley (Hordeum vulgare L.) (book review). Heredity 74: 5-16

Mutants generated by the insertion of random oligonucleotides into the active site of the b-lactamase gene. Biochemistry (American Chemical Society) 28: 03-7

Mutants in ABC10b, a conserved subunit shared by all three yeast RNA polymerases, specifically affect RNA polymerase I assembly. The Journal of Biological Chemistry 274(13): 21-7

Mutants in a macrophage-like cell line are defective in plasmalogen biosynthesis, but contain functional peroxisomes. Journal of Biological Chemistry 267(12): 8299-8306

Mutants in glucose metabolism. Annual Review of Biochemistry 55: 317-337

Mutants of Arabidopsis deficient in the synthesis of a-linolenate. Biochemical and genetic characterization of the endoplasmic reticulum linoleoyl desaturase. The Journal of Biological Chemistry 268: 345-51

Mutants of chinese hamster ovary cells affected in two different microtubule-associated proteins. Genetic and biochemical studies. Journal of Biological Chemistry 259(3): 1882-1890

Mutants of HLA-A2 in the analysis of its structure and function. Cold Spring Harbor Symposia on Quantitative Biology 54 Pt 1: 361-363

Mutants of Pseudomonas fluorescens NCIMB 11671 defective in the catabolism of a-pinene. Applied Microbiology and Biotechnology 45: 2-30

Mutants of S. cerevisiae defective in the maintenance of minichromosomes. Genetics 106(3): 365-385

Mutants of Streptococcus faecalis sensitive to alkaline pH lack Na(+)-ATPase. Journal of Bacteriology 172(4): 1732-1735

Mutants of maize (book review). The Quarterly Review of Biology 73(2): 7

Mutants of single chain interleukin 5 show asymmetric recruitment of receptor a and bc subunits. The Journal of Biological Chemistry 271: 729-34

Mutants of yeast Saccharomyces cerevisiae producing large amounts of the flavor components isobutyl alcohol and isoamyl alcohol. Agricultural and Biological Chemistry 54: 45-6

Mutants with changes within or near a hydrophobic region of simian virus 40 large tumor antigen are defective for binding cellular protein p53. Virology 168(1): 13-21

Mutated barley (1,3)-b- D-glucan endohydrolases synthesize crystalline (1,3)-b- D-glucans. The Journal of Biological Chemistry 277(33): 102-11

Mutated-c-actin restores growth to a yeast amino acid transport defective mutant. Journal of Cellular Physiology 186(1): 4-35

Mutation Analysis of the Functional Role of Amino Acid Residues in Domain IV of Elongation Factor G. Molecular Biology 40(5): 4-9

Mutation Lys758- >Ile of the sarcoplasmic reticulum Ca2+-ATPase enhances dephosphorylation of E2P and inhibits the P2 to E1Ca2 transition. The Journal of Biological Chemistry 272: 244-53

Mutation rate variation at human dinucleotide microsatellites. Genetics 170(1): 305-312

Mutation T318M in the CYP11B2 gene encoding P450c11AS (aldosterone synthase) causes corticosterone methyl oxidase II deficiency. American Journal of Human Genetics 57(5): 1037-1043

Mutation analysis of metallo-b-lactamase CcrA from Bacteroides fragilis. Biochemistry (American Chemical Society) 39(37): 330-9

Mutation analysis of very-long-chain acyl-coenzyme A dehydrogenase (VLCAD) deficiency: identification and characterization of mutant VLCAD cDNAs from four patients. American Journal of Human Genetics 58(1): 97-106

Mutation and adaptation: the directed mutation controversy in evolutionary perspective. Annual Review of Ecology and Systematics 26 : 3-78

Mutation and analysis of Dan, the founding member of the Dan family of transforming growth factor b antagonists. Molecular and Cellular Biology 21(2): 6-43

Mutation and evolution (book review). The Quarterly Review of Biology 75(3): 6

Mutation and the environment (book review). American Journal of Human Genetics 49: 8-9

Mutation at amino acid position 133 of H-2Dd prevents b2m association and immune recognition but not surface expression. Journal of Immunology 146: 52-7

Mutation at the Polymerase Active Site of Mouse DNA Polymerase Increases Genomic Instability and Accelerates Tumorigenesis. Molecular and Cellular Biology 27(21): 69-82

Mutation breeding (book review). The Journal of Agricultural Science 133 pt4: 1-2

Mutation causing autosomal dominant nocturnal frontal lobe epilepsy alters Ca2+ permeability, conductance, and gating of human a4/b2 nicotinic acetylcholine receptors. Journal of Neuroscience 17: 35-47

Mutation eliminating mitochondrial leader sequence of methylmalonyl-CoA mutase causes muto methylmalonic acidemia. Proceedings of the National Academy of Sciences of the United States of America 87(8): 3147-3150

Mutation in Cys662 of Escherichia coli DNA topoisomerase I confers temperature sensitivity and change in DNA cleavage selectivity. Journal of Molecular Biology 250(5): 609-616

Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine. Nature Genetics 19(3): 271-273

Mutation in Pseudomonas aeruginosa causing simultaneous defects in penicillin-binding protein 5 and in enzyme activities of penicillin release and D-alanine carboxypeptidase. Journal of Bacteriology 162(2): 849-851

Mutation in TRMU related to transfer RNA modification modulates the phenotypic expression of the deafness-associated mitochondrial 12S ribosomal RNA mutations. American Journal of Human Genetics 79(2): 291-302

Mutation in galactosemia. American Journal of Human Genetics 57: 8-9

Mutation in hepatocyte nuclear factor-1b gene (TCF2) associated with MODY. Nature Genetics 17: 4-5

Mutation in neurofilament transgene implicates RNA processing in the pathogenesis of neurodegenerative disease. Journal of Neuroscience 19(4): 1273-1283

Mutation in the Trapa/Ssr1 Gene, Encoding Translocon-Associated Protein a, Results in Outflow Tract Morphogenetic Defects. Molecular and Cellular Biology 26(20): 60-71

Mutation in the a5(IV) collagen chain in juvenile-onset Alport syndrome without hearing loss or ocular lesions: detection by denaturing gradient gel electrophoresis of a PCR product. American Journal of Human Genetics 50: 91-300

Mutation in the class II trans-activator leading to a mild immunodeficiency. Journal of Immunology 167(3): 1787-1794

Mutation in the gene encoding the a chain of platelet glycoprotein Ib in platelet-type von Willebrand disease. Proceedings of the National Academy of Sciences of the United States of America 88: 61-5

Mutation in the magnesium binding site of hMSH6 disables the hMutSa sliding clamp from translocating along DNA. The Journal of Biological Chemistry 275(3): 80-6

Mutation in the primer binding site of type 1 human immunodeficiency virus genome affects virus production and infectivity. Proceedings of the National Academy of Sciences of the United States of America 89: 14-18

Mutation in the specificity polypeptide of the type I restriction endonuclease R.EcoK that affects subunit assembly. Journal of Molecular Biology 227(3): 597-601

Mutation of 3' splice in two different class I genes results in different usage of cryptic splice sites. Journal of Immunology 143: 18-25

Mutation of Arg-54 strongly influences heme composition and rate and directionality of electron transfer in Paracoccus denitrificans cytochrome c oxidase. Journal of Biological Chemistry 274(53): 37974-37981

Mutation of Arg273 to Leu alters the specificity of the yeast N-glycan processing class I a1,2-mannosidase. The Journal of Biological Chemistry 275(15): 071-4

Mutation of Arginine 228 to Lysine Enhances the Glucosyltransferase Activity of Bovine b-1,4-Galactosyltransferase I. Biochemistry (American Chemical Society) 44(9): 02-10

Mutation of COOH-terminal lysines in overexpressed aB-crystallin abrogates ischemic protection in cardiomyocytes. American Journal of Physiology 283(1): 5-H91

Mutation of Cys672 allows recombinant expression of activatible macrophage-stimulating protein. Journal of Biological Chemistry 272(24): 15053-6

Mutation of Glutamate 155 of the GABAA Receptor b2 Subunit Produces a Spontaneously Open Channel: A Trigger for Channel Activation. Journal of Neuroscience 24(50): 226-35

Mutation of Leu-536 in Human Estrogen Receptor-a Alters the Coupling between Ligand Binding, Transcription Activation, and Receptor Conformation. The Journal of Biological Chemistry 278(29): 278-86

Mutation of PAX9 is associated with oligodontia. Nature Genetics 24(1):

Mutation of Tn5 Transposase b-Loop Residues Affects All Steps of Tn5 Transposition: The Role of Conformational Changes in Tn5 Transposition. Biochemistry (American Chemical Society) 45(51): 552-62

Mutation of a Conserved Asparagine in the I-like Domain Promotes Constitutively Active Integrins aLb2 and aIIbb3. The Journal of Biological Chemistry 282(25): 225-32

Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance. Molecular and Cellular Biology 24(8): 3497-3504

Mutation of a Src phosphorylation site in the PDGF b-receptor leads to increased PDGF-stimulated chemotaxis but decreased mitogenesis. The EMBO Journal 15: 99-313

Mutation of a conserved amino acid residue (tryptophan 1173) in the tyrosine kinase domain of the IGF-I receptor abolishes autophosphorylation but does not eliminate biologic function. Journal of Biological Chemistry 270(6): 2764-2769

Mutation of a cysteine in the first transmembrane segment of Na,K-ATPase a subunit confers ouabain resistance. The EMBO Journal 11: 81-7

Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulans. Cell 60(6): 1019-1027

Mutation of a ligand binding domain of b3 integrin. Integral role of oxygenated residues in aIIbb3 (GPIIb-IIIa) receptor function. The Journal of Biological Chemistry 269: 913-19

Mutation of a single conserved residue in VH complementarity-determining region 2 results in a severe Ig secretion defect. Journal of Immunology 167(4): 2179-2186

Mutation of a tyrosine in the H3-H4 ectodomain of Na,K-ATPase a subunit confers ouabain resistance. The Journal of Biological Chemistry 268: 722-6

Mutation of aPhe55 of Methylamine Dehydrogenase Alters the Reorganization Energy and Electronic Coupling for Its Electron Transfer Reaction with Amicyanin. Biochemistry (American Chemical Society) 41(47): 926-33

Mutation of an aspartate residue highly conserved among G-protein-coupled receptors results in nonreciprocal disruption of a2-adrenergic receptor-G-proteins interactions. A negative charge at amino acid residue 79 forecasts a2A-adrenergic receptor sensitivity to allosteric modulation by monovalent cations and fully effective receptor/G-protein coupling. The Journal of Biological Chemistry 269: 557-64

Mutation of arginine 44 of GAT-1, a (Na+ + Cl-)-coupled g-aminobutyric acid transporter from rat brain, impairs net flux but not exchange. The Journal of Biological Chemistry 275(44): 106-13

Mutation of glutamate 309 to glutamine alters one Ca(2+)-binding site in the Ca(2+)-ATPase of sarcoplasmic reticulum expressed in Sf9 cells. Journal of Biological Chemistry 268(21): 15944-15950

Mutation of glycine 185 to valine alters ATPase function of the human P-glycoprotein expressed in Sf9 cells. The Journal of Biological Chemistry 270: 86-90

Mutation of glycine 49 to valine in the a subunit of Gs results in the constitutive elevation of cyclic AMP synthesis. Biochemistry (American Chemical Society) 28: 47-51

Mutation of histidine 373 to leucine in cytochrome P450c17 causes 17a-hydroxylase deficiency. The Journal of Biological Chemistry 268: 811-17

Mutation of host 9 fatty acid desaturase inhibits brome mosaic virus RNA replication between template recognition and RNA synthesis. Journal of Virology 75(5): 97-106

Mutation of invariant cysteines of mammalian metallothionein alters metal binding capacity, cadmium resistance, and 113Cd NMR spectrum. Journal of Biological Chemistry 266(36): 24390-7

Mutation of proline 211 reduces shedding of the human p75 TNF receptor. Journal of Immunology 160(5): 2478-2487

Mutation of the RIIb subunit of protein kinase A differentially affects lipolysis but not gene induction in white adipose tissue. The Journal of Biological Chemistry 274(51): 281-7

Mutation of the SP1 sequence impairs both multimerization and membrane-binding activities of human immunodeficiency virus type 1 Gag. Journal of Virology 79(3): 1803-1812

Mutation of the a2A-Adrenoceptor Impairs Working Memory Performance and Annuls Cognitive Enhancement by Guanfacine. Journal of Neuroscience 22(19): 71-7

Mutation of the cytoplasmic domain of the integrin b3 subunit. Differential effects on cell spreading, recruitment to adhesion plaques, endocytosis, and phagocytosis. The Journal of Biological Chemistry 270: 50-7

Mutation of the endothelin-3 gene in the Waardenbug-Hirschsprung disease (Shah-Waardenburg syndrome). Nature Genetics 12: 2-4

Mutation of the fourth cytoplasmic loop of rhodopsin affects binding of transducin and peptides derived from the carboxyl-terminal sequences of transducing a and c subunits. The Journal of Biological Chemistry 275(3): 37-43

Mutation of the high cysteine region of the human insulin receptor a-subunit increases insulin receptor binding affinity and transmembrane signaling. The Journal of Biological Chemistry 264: 900-4

Mutation of the protein kinase C phosphorylation site on rat a1 Na+, K+-ATPase alters regulation of intracellular Na+ and pH and influences cell shape and adhesiveness. The Journal of Biological Chemistry 272: 179-84

Mutation of the proteolipid protein gene PLP in a human X chromosome-linked myelin disorder. Proceedings of the National Academy of Sciences of the United States of America 86(20): 8128-8131

Mutation of tyrosine-141 inhibits insulin-promoted tyrosine phosphorylation and increased responsiveness of the human b2-adrenergic receptor. The EMBO Journal 14: 42-9

Mutation of valine residue unique to a subunit of Gs abolishes activation. The Journal of Biological Chemistry 269: 899-904

Mutation prlF1 relieves the lethality associated with export of b-galactosidase hybrid proteins in Escherichia coli. Journal of Bacteriology 158: 8-83

Mutation rate in the hypervariable VNTR g3 (D7S22) is affected by allele length and a flanking DNA sequence polymorphism near the repeat array. American Journal of Human Genetics 59(2): 360-367

Mutation rates in diploid annuals- are they immutable?. International Journal of Plant Sciences 153: 2-5

Mutation spectrum following transfection of ultraviolet-irradiated single-stranded or double-stranded shuttle vector DNA into monkey cells. Journal of Molecular Biology 218(4): 667-673

Mutation studies in mung bean (Phaseolus aureus). Induced polygenic variability. Canadian Journal of Genetics and Cytology 25: 8-303

Mutation, developmental selection, and plant evolution (book review). The Quarterly Review of Biology 64: 0-1

Mutation-induced perturbation of the cytochrome c alkaline transition. Biochemistry 28(8): 3152-3156

Mutational analysis of intervening sequences connecting the binding sites for integration host factor, PepA, PurR, and RNA polymerase in the control region of the Escherichia coli carAB operon, encoding carbamoylphosphate synthase. Journal of Bacteriology 188(9): 3236-3245

Mutational Analysis of Roles for Extracellular Cysteine Residues in the Assembly and Function of Human a7-Nicotinic Acetylcholine Receptors. Biochemistry (American Chemical Society) 42(4): 0-6

Mutational Analysis of Target Enzyme Recognition of the b-Trefoil Fold Barley a-Amylase/Subtilisin Inhibitor. The Journal of Biological Chemistry 280(15): 855-64

Mutational Analysis of a-b Subunit Interactions in the Delivery of Na,K-ATPase Heterodimers to the Plasma Membrane. The Journal of Biological Chemistry 278(37): 794-803

Mutational Analysis of s70 Region 4 Needed for Appropriation by the Bacteriophage T4 Transcription Factors AsiA and MotA. Journal of Molecular Biology 363(5): 1-44

Mutational analysis of the conserved motif of the Arda anti-restriction protein encoded by self-transmissible IncI plasmid ColIb-p9. Molekuliarnaia Biologiia 36(6): 1062-1067

Mutational Analysis of the Critical Bases Involved in Activation of the AreR-Regulated s54-Dependent Promoter in Acinetobacter sp. Strain ADP1. Applied and Environmental Microbiology 69(9): 27-35

Mutational Analysis of the Folding Transition State of the C-Terminal Domain of Ribosomal Protein L9: A Protein with an Unusual b-Sheet Topology. Biochemistry (American Chemical Society) 46(4): 13-21

Mutational Analysis of the IFNAR1 Binding Site on IFNa2 Reveals the Architecture of a Weak Ligand-Receptor Binding-site. Journal of Molecular Biology 353(2): 1-81

Mutational analysis of the mechanism of negative regulation by SRC homology 2 domain-containing protein tyrosine phosphatase substrate-1 of phagocytosis in macrophages. Journal of Immunology 177(5): 3123-3132

Mutational Analysis of the Myxococcus xanthus Q4406 Promoter Region Reveals an Upstream Negative Regulatory Element That Mediates C-Signal Dependence. Journal of Bacteriology 188(2): 5-24

Mutational Analysis of the Promoter Recognized by Chlamydia and Escherichia coli s28 RNA Polymerase. Journal of Bacteriology 188(15): 24-31

Mutational analysis of the ribosome. Advances in Genetics 58: 89-119

Mutational Analysis of the a-1 Repeat of the Cardiac Na+-Ca2+ Exchanger. The Journal of Biological Chemistry 280(2): 61-9

Mutational analysis of the ompA promoter from Flavobacterium johnsoniae. Journal of Bacteriology 189(14): 5108-5118

Mutational interference and the progression of Muller's ratchet when mutations have a broad range of deleterious effects. Genetics 177(2): 971-986

Mutational Profiling in the Human Genome. Cold Spring Harbor Symposia on Quantitative Biology 68 2003: 9

Mutational analysis and characterization of the Escherichia coli hya operon, which encodes (NiFe) hydrogenase 1. Journal of Bacteriology 173(15): 51-61

Mutational analysis of 16S ribosomal RNA structure and function in Escherichia coli. Advances in Genetics 33: 1-39

Mutational analysis of 23S ribosomal RNA structure and function in Escherichia coli. Advances in Genetics 41: 157-195

Mutational analysis of CD28-mediated costimulation of Jun-N-terminal kinase and IL-2 production. Journal of Immunology 161(10): 5366-5372

Mutational analysis of G protein a subunit Goa expressed in Escherichia coli. The Journal of Biological Chemistry 268: 14-23

Mutational analysis of Gbc and phospholipid interaction with G protein-coupled receptor kinase 2. The Journal of Biological Chemistry 275(14): 443-52

Mutational analysis of Hsp90a dimerization and subcellular localization: dimer disruption does not impede 'in vivo' interaction with estrogen receptor. Journal of Cell Science 109: 77-87

Mutational analysis of TNF-a gene reveals a regulatory role for the 3'-untranslated region in the genetic predisposition to lupus-like autoimmune disease. Journal of Immunology 156: 43-50

Mutational analysis of Tyr-318 within the non-nucleoside reverse transcriptase inhibitor binding pocket of human immunodeficiency virus type I reverse transcriptase. Journal of Biological Chemistry 273(51): 34234-9

Mutational analysis of a site-specific recombinase: characterization of the catalytic and dimerization domains of the b recombinase of pSM19035. Molecular and General Genetics 255(5): 7-76

Mutational analysis of a-subunit of protein farnesyltransferase. Evidence for a catalytic role. The Journal of Biological Chemistry 268: 83-90

Mutational analysis of arsonate binding by a CRIA+ antibody. VH and VL junctional diversity are essential for binding activity. Journal of Biological Chemistry 266(12): 7626-7632

Mutational analysis of avidity and fine specificity of anti-levan antibodies. Journal of Immunology 163(12): 6694-6701

Mutational analysis of b'260-309, a s70 binding site located on Escherichia coli core RNA polymerase. The Journal of Biological Chemistry 275(30): 113-19

Mutational analysis of bacteriophage T4 AsiA: involvement of N- and C-terminal regions in binding to s70 of Escherichia coli in vivo. Gene 295(1): 5-34

Mutational analysis of conserved residues of the b-subunit of human farnesyl:protein transferase. The Journal of Biological Chemistry 272: 319-23

Mutational analysis of domain IIb of bacteriophage Mu transposase: domains IIa and IIb belong to different catalytic complementation groups. Journal of Molecular Biology 275: 1-32

Mutational analysis of duck d2 crystallin and the structure of an inactive mutant with bound substrate provide insight into the enzymatic mechanism of argininosuccinate lyase. The Journal of Biological Chemistry 277(6): 66-75

Mutational analysis of essential IncPa plasmid transfer genes traF and traG and involvement of traF in phage sensitivity. Journal of Bacteriology 174(20): 66-73

Mutational analysis of interferon (IFN) regulatory factors 1 and 2. Effects on the induction of IFN-b gene expression. The Journal of Biological Chemistry 269: 542-9

Mutational analysis of ligand binding activity of b2 adrenergic receptor expressed in Escherichia coli. The EMBO Journal 9: 79-84

Mutational analysis of mammalian translation initiation factor 5 (eIF5): role of interaction between the b subunit of eIF2 and eIF5 in eIF5 function in vitro and in vivo. Molecular and Cellular Biology 20(11): 42-50

Mutational analysis of motor proteins. Annual Review of Physiology 58: 751-792

Mutational analysis of muscarinic acetylcholine receptors: structural basis of ligand/receptor/G protein interactions. Life Sciences 53(19): 1447-1463

Mutational analysis of o29 DNA polymerase residues acting as ssDNA ligands for 3'-5' exonucleolysis. Journal of Molecular Biology 279(4): 7-22

Mutational analysis of plasminogen activator inhibitor-1. Interactions of a-helix F and its neighbouring structural elements regulates the activity and the rate of latency transition. European Journal of Biochemistry 270(8): 80-8

Mutational analysis of poliovirus 2Apro. Distinct inhibitory functions of 2apro on translation and transcription. Journal of Biological Chemistry 273(43): 27960-7

Mutational analysis of the A-kinase anchoring protein (AKAP)-binding site on RII. Classification Of side chain determinants for anchoring and isoform selective association with AKAPs. Journal of Biological Chemistry 271(46): 29016-29022

Mutational analysis of the DNA polymerase and ribonuclease H activities of human immunodeficiency virus type 2 reverse transcriptase expressed in Escherichia coli. Virology 180(1): 339-346

Mutational analysis of the Golgi retention signal of bovine b-1,4-galactosyltransferase. The Journal of Biological Chemistry 268: 08-16

Mutational analysis of the PapB transcriptional regulator in Escherichia coli. Regions important for DNA binding and oligomerization. Journal of Biological Chemistry 274(28): 19723-19730

Mutational analysis of the Ricinus lectin B-chains. Galactose-binding ability of the 2c subdomain of Ricinus communis agglutinin B-chain. The Journal of Biological Chemistry 270: 292-7

Mutational analysis of the Streptomyces lividans recA gene suggests that only mutants with residual activity remain viable. Molecular & General Genetics 255(4): 420-428

Mutational analysis of the b-subunit of yeast geranylgeranyl transferase I. Molecular and General Genetics 252: 10

Mutational analysis of the biglycan gene excludes it as a candidate for X-linked dominant chondrodysplasia punctata, dyskeratosis congenita, and incontinentia pigmenti. American Journal of Human Genetics 54(5): 922-925

Mutational analysis of the consensus nucleotide binding sequences in the rat liver mitochondrial ATP synthase b-subunit. The Journal of Biological Chemistry 267: 331-8

Mutational analysis of the conserved cationic residues of Bacillus stearothermophilus 6-phosphoglucose isomerase. European Journal of Biochemistry 257(2): 500-505

Mutational analysis of the fine specificity of binding of monoclonal antibody 51F to l repressor. The Journal of Biological Chemistry 264: 355-60

Mutational analysis of the herpes simplex virus type 1 ICP0 C3HC4 zinc ring finger reveals a requirement for ICP0 in the expression of the essential a27 gene. Journal of Virology 71: 02-14

Mutational analysis of the human DNA polymerase a. The most conserved region in a-like DNA polymerases is involved in metal-specific catalysis. The Journal of Biological Chemistry 268: 028-40

Mutational analysis of the human HSP70 protein: distinct domains for nucleolar localization and adenosine triphosphate binding. Journal of Cell Biology 109(5): 1947-1962

Mutational analysis of the human mitochondrial genome branches into the realm of bacterial genetics. American Journal of Human Genetics 59(4): 749-755

Mutational analysis of the integrase protein of human immunodeficiency virus type 2. Proceedings of the National Academy of Sciences of the United States of America 89(20): 9598-9602

Mutational analysis of the ligand-binding domain of M-T2 protein, the tumor necrosis factor receptor homologue of myxoma virus. Journal of Immunology 157(10): 4486-4495

Mutational analysis of the mRNA operator for T4 DNA polymerase. Genetics 128(2): 203-213

Mutational analysis of the nucleic acid-binding 17 kDa phosphoprotein of potato leafroll luteovirus identifies an amphipathic a-helix as the domain for protein/protein interactions. Virology 4-82

Mutational analysis of the pleckstrin homology domain of the b-adrenergic receptor kinase. Differential effects on Gbc and phosphatidylinositol 4,5-bisphosphate binding. The Journal of Biological Chemistry 270: 000-5

Mutational analysis of the potential phosphorylation sites in the cytoplasmic domain of integrin b1A. Requirement for threonines 788-789 in receptor activation. Journal of Cell Science 111(8): 17-26

Mutational analysis of the prohead binding domain of the large subunit of terminase, the bacteriophage l DNA packaging enzyme. Journal of Molecular Biology 245: 6-40

Mutational analysis of the promoter region of the a27 gene of herpes simplex virus 1 within the context of the viral genome. Proceedings of the National Academy of Sciences of the United States of America 87(14): 68-72

Mutational analysis of the properties of caveolin-1. A novel role for the C-terminal domain in mediating homo-typic caveolin interactions. The Journal of Biological Chemistry 272: 98-403

Mutational analysis of the ribonuclease H activity of human immunodeficiency virus 1 reverse transcriptase. Virology 175(2): 575-580

Mutational analysis of the role of the first helix of region 4.2 of the s70 subunit of Escherichia coli RNA polymerase in transcriptional activation by activator protein PhoB. Molecular and General Genetics 248: 8

Mutational analysis of the sequence encoding ICP0 from herpes simplex virus type 1. Virology 180(1): 207-220

Mutational analysis of the superantigen staphylococcal exfoliative toxin A (ETA). Journal of Immunology 164(4): 2207-2213

Mutational analysis of two DRa residues involved in dimers of HLA-DR molecules. Journal of Immunology 155: 10-17

Mutational analysis of yeast RNA triphosphatases highlight a common mechanism of metal-dependent NTP hydrolysis and means of targeting enzymes to pre-mRNAs in vivo by fusion to the guanylyltransferase component of capping apparatus. The Journal of Biological Chemistry 274(41): 865-74

Mutational analysis of yeast vacuolar H(+)-ATPase. Proceedings of the National Academy of Sciences of the United States of America 88(5): 1938-1942

Mutational analysis reveals multiple distinct sites within Fcc receptor IIB that function in inhibitory signaling. Journal of Immunology 165(8): 53-62

Mutational and Structural Analysis of Aglycone Specificity in Maize and Sorghum b-Glucosidases. The Journal of Biological Chemistry 278(27): 055-62

Mutational and X-ray crystallographic analysis of the interaction of dihomo-c-linolenic acid with prostaglandin endoperoxide H synthases. The Journal of Biological Chemistry 276(13): 358-65

Mutational and comparative analysis of streptolysin O, an oxygen-labile streptococcal hemolysin. Bioscience, Biotechnology, and Biochemistry 65(12): 82-9

Mutational and computational analysis of the a1b-adrenergic receptor. Involvement of basic and hydrophobic residues in receptor activation and G protein coupling. The Journal of Biological Chemistry 276(49): 485-94

Mutational and structural analysis of the nitrate reductase heme of Nicotiana plumbaginifolia. The Journal of Biological Chemistry 266: 561-6

Mutational effects on protein stability. Annual Review of Biochemistry 58: 765-798

Mutational events in consecutive passages of hepatitis A virus strain GBM during cell culture adaptation. Virology 204(1): 60-68

Mutational hot spots in the mitochondrial microcosm. American Journal of Human Genetics 59(3): 493-496

Mutational hotspot variability in an ultraviolet-treated shuttle vector plasmid propagated in xeroderma pigmentosum and normal human lymphoblasts and fibroblasts. Journal of Molecular Biology 212(3): 433-436

Mutational replacements of conserved amino acid residues in the b subunit resulted in defective assembly of H+-translocating ATPase (F0F1) in Escherichia coli. The Journal of Biological Chemistry 261: 70-5

Mutational site in tunicamycin-resistant mutation tmrB8 of Bacillus subtilis as revealed at the nucleotide sequence level. Agricultural and Biological Chemistry 52: 3-4

Mutational specificity in bacteria. Annual Review of Genetics 17: 215-238

Mutational studies of human DNA polymerase a. Identification of residues critical for deoxynucleotide binding and misinsertion fidelity of DNA synthesis. The Journal of Biological Chemistry 268: 163-74

Mutational studies of human DNA polymerase a. Lysine 950 in the third most conserved region of a-like DNA polymerases is involved in binding the deoxynucleoside triphosphate. The Journal of Biological Chemistry 270: 563-70

Mutational studies of human DNA polymerase a. Serine 867 in the second most conserved region among a-like DNA polymerases is involved in primer binding and mispair primer extension. The Journal of Biological Chemistry 268: 175-82

Mutational study on the roles of disulfide bonds in the b-subunit of gastric H+,K+-ATPase. The Journal of Biological Chemistry 277(23): 671-7

Mutations conferring resistance to human immunodeficiency virus type 1 fusion inhibitors are restricted by gp41 and Rev-responsive element functions. Journal of Virology 79(2): 764-770

Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways. Molecular and Cellular Biology 24(8): 3295-3306

Mutations Near Amino End of a1(I) Collagen Cause Combined Osteogenesis Imperfecta/Ehlers-Danlos Syndrome by Interference with N-propeptide Processing. The Journal of Biological Chemistry 280(19): 259-69

Mutations That Rescue the Paralysis of Caenorhabditis elegans ric-8 (Synembryn) Mutants Activate the Gas Pathway and Define a Third Major Branch of the Synaptic Signaling Network. Genetics 169(2): 1-49

Mutations abolishing the endonuclease activity of bacteriophage l terminase lie in two distinct regions of the A gene, one of which may encode a leucine zipper DNA-binding domain. Virology 189: 30

Mutations affecting assembly of b-tubulin localize to a region near the carboxyl terminus. The Journal of Biological Chemistry 263: 566-73

Mutations affecting conformation or sequence of neutralizing epitopes identified by reactivity of viable plaques segregate from syn and ts domains of HSV-1(F) gB gene. Virology 135(2): 379-394

Mutations affecting lysine-35 of gpNu1, the small subunit of bacteriophage l terminase alter the strength and specificity of holoterminase interactions with DNA. Virology 231: 8-30

Mutations affecting pore formation by haemolysin from Escherichia coli. Molecular & General Genetics 226(1-2): 198-208

Mutations affecting the catalytic activity of Bacillus cereus 5/B/6 b-lactamase II. The Journal of Biological Chemistry 264: 682-7

Mutations affecting the cytochrome d-containing oxidase complex of Escherichia coli K12: identification and mapping of a fourth locus, cydD. Journal of General Microbiology 135(7): 1865-1874

Mutations affecting the high affinity ATPase center of gpA, the large subunit of bacteriophage l terminase, inactivate the endonuclease activity of terminase. Journal of Molecular Biology 261: 4-35

Mutations altering heat shock specific subunit of RNA polymerase suppress major cellular defects of E. coli mutants lacking the DnaK chaperone. Embo Journal 9(12): 4027-4036

Mutations and rearrangements in the genome of Sulfolobus solfataricus P2. Journal of Bacteriology 188(12): 4198-4206

Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid b-protein precursor. The Journal of Biological Chemistry 269: 741-8

Mutations at Glu-32 and His-39 in the e subunit of the Escherichia coli F1F0 ATP synthase affect its inhibitory properties. Journal of Bacteriology 174(2): 3-7

Mutations at Leucine 215 of b-Tubulin Affect Paclitaxel Sensitivity by Two Distinct Mechanisms. Biochemistry (American Chemical Society) 45(1): 5-94

Mutations at domain II, loop 3, of Bacillus thuringiensis CryIAa and CryIAb d-endotoxins suggest loop 3 is involved in initial binding to lepidopteran midguts. The Journal of Biological Chemistry 271: 220-6

Mutations at the domain interface of Gsa impair receptor-mediated activation by altering receptor and guanine nucleotide binding. The Journal of Biological Chemistry 273(24): 053-60

Mutations away from splice site recognition sequences might cis-modulate alternative splicing of goat as1-casein transcripts. Structural organization of the relevant gene. The Journal of Biological Chemistry 267: 47-57

Mutations in 16S rRNA that affect UGA (stop codon)-directed translation termination. Proceedings of the National Academy of Sciences of the United States of America 88(15): 6603-6607

Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating b-catenin/TCF signalling. Nature Genetics 26(2): 6-7

Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy. American Journal of Human Genetics 81(2): 280-291

Mutations in GCD11, the structural gene for eIF-2c in yeast, alter translational regulation of GCN4 and the selection of the start site for protein synthesis. The EMBO Journal 14: 39-49

Mutations in GJB6 cause nonsyndromic autosomal dominant deafness at DFNA3 locus. Nature Genetics 23(1): 16-18

Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa. Nature Genetics 26(3): 270-271

Mutations in MKKS cause Bardet-Biedl syndrome. Nature Genetics 26(1): 15-16

Mutations in paramecium calmodulin indicate functional differences between the C-terminal and N-terminal lobes in vivo. Cell 62(1): 165-174

Mutations in RGR, encoding a light-sensitive opsin homologue, in patients with retinitis pigmentosa. Nature Genetics 23(4): 393-394

Mutations in SDHC cause autosomal dominant paraganglioma, type 3. Nature Genetics 26(3): 268-270

Mutations in SIP1, encoding Smad interacting protein-1, cause a form of Hirschsprung disease. Nature Genetics 27(4): 369-370

Mutations in SLC4A4 cause permanent isolated proximal renal rubular acidosis with ocular abnormalities. Nature Genetics 23(3): 4-6

Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome. Nature Genetics 25(2): 141-142

Mutations in Ser174 and the glycine-rich sequence (Gly149, Gly150, and Thr156) in the b subunit of Escherichia coli H+-ATPase. The Journal of Biological Chemistry 266: 350-5

Mutations in a D8-D7 sterol isomerase in the tattered mouse and X-linked dominant chondrodysplasia punctata. Nature Genetics 22(3): 6-90

Mutations in a novel cochlear gene cause DFNA9, a human nonsyndromic deafness with vestibular dysfunction. Nature Genetics 20(3): 299-303

Mutations in a putative global transcriptional regulator cause X-linked mental retardation with a-thalassemia (ATR-X syndrome). Cell 80: 7-45

Mutations in a signalling pathway. Nature 436: 2

Mutations in a- and B-tubulin affect spindle formation in Chinese hamster ovary cells. The Journal of Cell Biology 97: 55-61

Mutations in a-Chain of C4BP That Selectively Affect Its Factor I Cofactor Function. The Journal of Biological Chemistry 278(44): 437-42

Mutations in a-Tubulin Cause Abnormal Neuronal Migration in Mice and Lissencepaly in Humans. Cell 128(1): 57

Mutations in acid b-galactosidase cause GM1-gangliosidosis in American patients. American Journal of Human Genetics 53: 1-8

Mutations in and monoclonal antibody binding to evolutionary hypervariable region of Escherichia coli RNA polymerase b' subunit inhibit transcript cleavage and transcript elongation. The Journal of Biological Chemistry 273(38): 912-20

Mutations in b-myosin S2 that cause familial hypertrophic cardiomyopathy (FHC) abolish the interaction with the regulatory domain of myosin-binding protein-C. Journal of Molecular Biology 286(3): 3-49

Mutations in bacteriophage l repressor that prevent RecA-mediated cleavage. Journal of Bacteriology 162: 7-54

Mutations in bacteriophage l that alter phage dependence on the htpR gene product of Escherichia coli. Virology 149: 8-31

Mutations in collagen genes: causes of rare and some common diseases in humans. Faseb Journal 5(7): 2052-2060

Mutations in domain I of Bacillus thuringiensis d-endotoxin CryIAb reduce the irreversible binding of toxin to Manduca sexta brush border membrane vesicles. The Journal of Biological Chemistry 270: 12-19

Mutations in domain IIIa of the Mu transposase: evidence suggesting an active site component which interacts with the Mu-host junction. Journal of Molecular Biology 282(2): 5-74

Mutations in elongation factor 1b, a guanine nucleotide exchange factor, enhance translation fidelity. Molecular and Cellular Biology ): 57-66

Mutations in elongation factor EF-1a affect the frequency of frameshifting and amino acid misincorporation in Saccharomyces cerevisiae. Genetics 120: 3-34

Mutations in fibroblast growth factor receptors: phenotypic consequences during eukaryotic development. American Journal of Human Genetics 57(4): 748-754