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Network communications: lymphotoxins, LIGHT, and TNF

, : Network communications: lymphotoxins, LIGHT, and TNF. Annual Review of Immunology 23: 787-819

Lymphotoxins (LT) provide essential communication links between lymphocytes and the surrounding stromal and parenchymal cells and together with the two related cytokines, tumor necrosis factor (TNF) and LIGHT (LT-related inducible ligand that competes for glycoprotein D binding to herpesvirus entry mediator on T cells), form an integrated signaling network necessary for efficient innate and adaptive immune responses.


PMID: 15771586

DOI: 10.1146/annurev.immunol.23.021704.115719

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