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A role of transplantation of hemopoetic stem cells in the treatment of patients with multiple sclerosis

, : A role of transplantation of hemopoetic stem cells in the treatment of patients with multiple sclerosis. Zhurnal Nevrologii I Psikhiatrii imeni S S Korsakova (Suppl. 4): 122-128

Autologous peripheral blood stem transplantation in 12 patients with multiple sclerosis is performed and clinical efficacy measures as well as magnetic resonance imaging and cerebrospinal fluid data before the treatment and during 1 to 2 years of prospective assessment are analyzed. The safety data and adverse events during the period of observation are presented. A comparison group comprised 25 patients with multiple sclerosis treated with interferon beta. Indications and limitations of autologous peripheral blood stem transplantation in patients with multiple sclerosis are discussed.


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