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CAMP - independent oscillations of adenylate cyclase in Dictyostelium discoideum


, : CAMP - independent oscillations of adenylate cyclase in Dictyostelium discoideum. Developmental Biology, 792: 500-507

In starved D. discoideum amoebae, extracellular cAMP appears to regulate adenylate cyclase activity such that synthesis of cAMP is rhythmic. Periodic modulation of adenylate cyclase also occurs via a cAMP-independent mechanism. This was demonstrated using cells which have high levels of adenylate cyclase activity, as measured in cell extracts, but which do not express this enzymic potential when intact. Such cells still rhythmically modify their adenylate cyclase activity and both the periodicity and the amplitude of the oscillations are similar to those seen in cells actively synthesizing cAMP. The phenomenon is observed using both wild-type cells and certain aggregation-minus mutants. A mechanism is implicated which is cAMP independent in the regulation of adenylate cyclase as well as in the synchrony of the cell population.

US$29.90

PMID: 6253338


Other references

Wallace, E.W.; Van Dyke, H.B., 1933: Cumulative poisoning by squill derivatives and by ouabain. Cumulation exps. on 48 dogs were performed with ouabain, 1 tincture of digitalis, and 4 derivatives of squill (2 crystalline, 2 amorphous), each animal receiving a daily intraven. dose of a glucoside until death occurred. Electrocardiograms were m...

Yates, S.P.; Otley, M.D.; Dawson, J.F., 2007: Overexpression of cardiac actin with baculovirus is promoter dependent. The influence of the promoter and an N-terminal hexahistidine tag on human cardiac actin (ACTC) expression and function was investigated using four baculovirus constructs. It was found that both non-tagged ACTC and hisACTC expression from the p10...

Jacob, S.; Shahzad, M.A.; Maheshwari, R.; Panaich, S.S.; Aravindhakshan, R., 2011: Cardiac rhythm device identification algorithm using X-Rays: CaRDIA-X. Heart Rhythm 8(6): 915-922

Simpkins William W.; Gustavson Thomas C., 1984: Rates of hillslope erosion and deposition at six stations on the High Plains and rolling plains of the Texas Panhandle, 1978-1982. Abstracts with Programs - Geological Society of America 16(4): 256

Almendro-Delia, M.; Blanco Ponce, E.; Gomez-Domínguez, Río.; Gonzalez-Matos, C.; Lobo-Gonzalez, M.; Caballero-Garcia, A.; Hidalgo-Urbano, R.; Cruz-Fernandez, M.Jose.; Garcia-Rubira, J.C., 2016: Safety and efficacy of in-hospital clopidogrel-to-prasugrel switching in patients with acute coronary syndrome. An analysis from the 'real world'. Antiplatelet switching in the management of acute coronary syndrome (ACS) seems to be safe, but prospective data are limited. This retrospective study assessed the safety and efficacy of in-hospital clopidogrel-to-prasugrel switching in patients w...

While, A., 2003: Getting the message across: Valuing People. British Journal of Community Nursing 8(11): 532-532

Persson, T.; Lindberg, N., 1999: Klimaeffekter pa hoppstjartar och kvalster i skogsmark. Vaxtskyddsnotiser 63(3): 48-52

Kaydash, V.; Kreslavsky, M.; Shkuratov, Yu; Gerasimenko, S.; Pinet, P.; Josset, J.L.; Beauvivre, S.; Foing, B., 2009: Photometric anomalies of the lunar surface studied with SMART-1 AMIE data. We present new results from the mapping of lunar photometric function parameters using images acquired by the spacecraft SMART-1 (European Space Agency). The source data for selected lunar areas imaged by the AMIE camera of SMART-1 and the data pr...

Datta, A.K.; Stephens, J.A., 1990: Synchronization of motor unit activity during voluntary contraction in man. 1. Motor unit synchronization has been studied in human first dorsal interosseous muscle. 2. Two needle electrodes were inserted into the muscle and the activity of pairs of motor units recorded. 3. Pre- and post-stimulus histograms of the firing...

Riedel, J.; Neudorf, U.; Schmaltz, A.A., 1997: Rapid progression of hypertrophic cardiomyopathy into a dilated form--unusual course in a young patient. A case report. Hypertrophic cardiomyopathy is a disorder which primarily affects the myocardium. It is characterized by a hypertrophic left ventricle that shows normal systolic function but impaired diastolic relaxation. The most important complication of HCM, s...