+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Quality of life in rhinoconjunctivitis assessed with generic and disease-specific questionnaires

, : Quality of life in rhinoconjunctivitis assessed with generic and disease-specific questionnaires. Allergy 63(3): 284-291

Background: Illness as perceived by the allergic patient with asthma and/or rhinoconjunctivitis (RC) can be assessed by measurements of their health-related quality of life (HRQL). For this purpose the RC Quality of Life Questionnaire (RQLQ) has gained general acceptance; however, as most allergic patients experience symptoms from multiple organs, disease-specific HRQL measures may be deficient. This study compares a generic and a disease-specific HRQL instrument in grass and/or mite-allergic patients.Methods: Two hundred and forty-eight patients with RC and 121 patients with both RC and asthma were studied. Questionnaire information was obtained about allergy-related RQLQ and a generic 15-dimensional instrument for measuring HRQL (15D). Doctors provided general and disease-specific information to classify disease severity according to the global initiative for asthma and allergic rhinitis and its impact on asthma guidelines.Results: Rhinoconjunctivitis patients with persistent moderate-to-severe disease had an impaired quality of life on all items of RQLQ during allergen exposure. The 15D mean score was 0.98 on a day without allergy and 0.83 on a day with allergy (P < 0.001). The correlation between 15D and RQLQ was r = -0.42 on a day with allergy (P < 0.001). Only 15D scores showed statistically significant differences in HRQL between patients with and without asthma.Conclusion: During allergen exposure patients with RC experience a serious deterioration in HRQL measured with the disease-specific RQLQ instrument and the generic 15D instrument. The 15D instrument seems to generate a more comprehensive view of the impact of allergen exposure on patient's quality of life than RQLQ.


PMID: 18269674

DOI: 10.1111/j.1398-9995.2007.01583.x

Other references

Hansen, J.L., 1948: The drawbacks encountered in local treatment of pleural empyema with chemotherapeutic and antibiotic agents. Acta Chirurgica Scandinavica 96(6): 509-529

Green, M., 1962: Review of Living with Reptiles by Kathleen Pickard-Smith. Britrpet: 61

Vesth, B., 1975: Crossbreeding studies with Red Danish and Red West Flemish cattle. This report describes an experiment to improve beef production characters for Danish Red (RDM) cattle, using 2 West Flemish Red (RBK) bulls, one of which gave very poor results in terms of milk and fat yields. The experiment was made with F1 (50%...

Williams, W.P.; Buckley, P.M.; Taylor, V.N., 1983: Southwestern corn borer growth on callus initiated from corn genotypes with different levels of resistance to plant damage. Callus from embryos of seven maize hybrids in one experiment and eight in another was initiated and maintained on medium with an addition of 14 mg/l 2,4-D. When ~600 mg of callus had developed on each Petri plate, three first-instar larvae of Diat...

Mukai, K.; Miyazaki, T.; Wakabayashi, S.; Kuramitsu, S.; Matsubara, H., 1985: Dissociation of bovine cytochrome c1 subcomplex and the status of cysteine residues in the subunits. Purified bovine heart two-band cytochrome c1 subcomplex was dissociated by treatment with p-chloromercuribenzoic acid (pCMB) into its heme subunit and a colorless subunit called hinge protein, which is essential for the formation of cytochrome c1-...

Bayraktar, Z.; Inan, E.Hacer.; Bayraktar, V., 2012: Effect of constipation on serum total prostate-specific antigen levels in men. Many factors affecting serum prostate-specific antigen (PSA) levels have been described. The aim of this study was to examine the effect of constipation on serum PSA levels in men. Serum total PSA values were measured in 136 constipated patients b...

Kingma; Hemley; Mao; Veblen, 1994: Kingma et al. reply. Physical Review Letters 72(8): 1302-1302

Iriuchijima, J., 1973: 115. Sympathetic tone in the spontaneously hypertensive rat. Nihon Seirigaku Zasshi. Journal of the Physiological Society of Japan 35(8): 430-430

Krantz, G.S., 1977: A revision of australopithecine body sizes. When Australopithecus dentitions are divided into A. africanus and A. robustus on morphological grounds alone it is found that both species are found in each of the major South African sites. There is a great sexual dimorphism in both species with...

Booth, I.R.; Kroll, R.G.; Findlay, M.J.; Stewart, L.M.; Rowland, G.C., 1984: Properties and physiology of energy-coupled mutants of Escherichia coli. Biochemical Society Transactions 12(3): 409-411