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Solid-phase synthesis and biological evaluation of a uridinyl branched peptide urea library

, : Solid-phase synthesis and biological evaluation of a uridinyl branched peptide urea library. Bioorganic & Medicinal Chemistry Letters 17(24): 6899-6904

A 1000-member uridinyl branched peptide library was synthesized on PS-DES support using IRORI technology. High-throughput screening of this library for anti-tuberculosis activity identified several members with a MIC(90) value of 12.5 microg/mL.


PMID: 17962016

DOI: 10.1016/j.bmcl.2007.09.097

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