+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Trends in prostate-specific antigen testing from 1995 through 2004

, : Trends in prostate-specific antigen testing from 1995 through 2004. Archives of Internal Medicine 167(22): 2497-2502

Background: The utility of the prostate-specific antigen (PSA) test to screen for prostate cancer has been widely debated for several years. Whether PSA testing rates have changed during this period of controversy is not well known.Methods: We examined the National Ambulatory Medical Care Survey (1995-2004) of visits to primary care providers by healthy men aged 35 years or older. We examined visits by calendar year and compared the years 2000 through 2004 with the years 1995 through 1999. We also examined visits by men in the overall population and in particular subgroups.Results: Primary care physicians ordered PSA tests in 4.7% of all visits in 1995 and in 7.0% of all visits in 2004 (P=.03). In multivariate analysis, the odds of a primary care physician ordering a PSA test during any clinic visit increased 8%( odds ratio [ OR], 1.08; 95% confidence interval [CI], 1.04-1.12; P <.001) per year from 1995 through 2004. The increase was more pronounced among men making visits for general medical examinations (11.2% in 1995 vs 32.3% in 2004; P=.003). Comparing the period 2000-2004 with the period 1995-1999, the odds of PSA testing increased in nearly all subgroups but most dramatically in black men ( OR, 2.3; 95% CI, 1.4-3.8; P=.002) and in men 35 through 49 years of age ( OR, 1.8; 95% CI, 1.3-2.6; P=.001).Conclusion: In a nationally representative sample, we found that despite the lack of clear evidence of benefit, PSA testing for prostate cancer screening has increased dramatically, especially among black men and younger men.


PMID: 18071173

DOI: 10.1001/archinte.167.22.2497

Other references

Inglis, WG., 1983: The design of the nematode body wall: the ontogeny of the cuticle. Hypotheses are presented which explain how the one-cell-thick nematode epidermis determines the structure of the complex proteinaceous cuticle during its ontogeny. The pseudometamerism, 3 major layers, and all radial structures, it is concluded, a...

Rieger, H.J., 1978: "Selling" body parts to the drug industry. Deutsche Medizinische Wochenschrift 103(7): 290-292

Fernández, M.; Del Castillo, J.L.; Nieto, M.J., 2015: Surgical Gown's Cuff Modification to Prevent Surgical Contamination. The gown-glove interface is the weakest point in the barrier system of gown and glove protection for the surgeon. We are herein presenting an easy modification in the cuff of the gown that increases the security of the gown-glove interface.

Ross, J.S.; Sheehan, C.E.; Karikehalli, S.; Azumi, N.; Kallakury, B.V.S., 2002: Co-expression of matrix metalloproteinases and poor prognostic significance in renal cell carcinomas. Proceedings of the American Association for Cancer Research Annual Meeting 43: 398, March

Kettman, J.; Burnham, K.; Lefkovits, I., 1988: Prospective partition analysis of independently assorted sets. Accessory elements supporting clonal lymphoid activation by mitogens. Accessory cells for mitogen-induced clonal proliferation of lymphocytes can be found after in vitro culture of murine spleen cells. Mitogenic activation of T cells (concanavalin A) depends on such accessory cells. When the cultures in which the ac...

Nagarajarao, Y.; Ramana, C.V., 1992: Moisture stress characterization in chickpea by canopy temperature and leaf water potential. In a field study on alluvial sandy loam soil (Typic Ustochrept) during the 1987/88 rabi [winter] season at New Delhi chickpeas cv. BG-261 and BG-209 grown with or without irrigation, leaf water potential (LWP) was negatively correlated to vapour p...

Leschot, N.J., 1993: Chromosome translocation in a DES-daughter: an incidental finding?. Nederlands Tijdschrift Voor Geneeskunde 137(32): 1585-1587

Dalkidis, C.; Kuenkel, S.; Eckert, R.; Thiem, S., 2004: Apparatus for treating objects. An apparatus for treating objects, in particular cytological or histological specimens, having multiple processing stations and preferably a transport device for delivering the objects into and out of the processing stations, is characterized in t...

Chen, K.C.; Krause, R.M., 1975: A peptide mapping technique--a three map system. Analytical Biochemistry 69(1): 180-186

Greene E.L.; Paller M.S., 1992: Xanthine oxidase produces superoxide radical in posthypoxic injury of renal epithelial cells. The hypothesis that posthypoxic renal injury is mediated by xanthine oxidase-derived oxygen free radical production was tested in an in vitro model of rat proximal tubule epithelial cells in primary culture subjected to 60 min of hypoxia and 30 mi...