geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Visceral obesity and the heart


, : Visceral obesity and the heart. International Journal of Biochemistry & Cell Biology 40(5): 821-836

Obesity and particularly its deleterious form, visceral adiposity, has reached a high prevalence in the industrialized world owing to the lack of exercise and the widely available energy-dense diet. As a consequence, cardiovascular diseases and metabolic disorders are afflicting an unprecedented number of individuals at a world-wide scale. Over the last decades, investigations have established firm links between visceral obesity and the development of cardiovascular diseases. Moreover, studies in the field of lipid partitioning have demonstrated that inadequacy of homeostatic mechanism ensuring adequate handling of energy surplus is associated with accumulation of visceral fat and lipid overload of internal organs, which are participating to the development of heart diseases. Visceral obesity and its metabolic consequences often referred to as the metabolic syndrome is associated with the production of an atherosclerosis prone milieu. In this review, clinical implications of visceral obesity on the development of cardiovascular disorders are reviewed along with important mechanisms participating to the development of these disorders. Implications and failure of lipid partitioning and some of the potential pathways mediating development of heart diseases are also covered in view of recent development of therapeutic options.

US$19.90

PMID: 18201922

DOI: 10.1016/j.biocel.2007.12.001


Other references

Danish G.Ya, 1974: Main manifestations of cardio vascular pathology in the terminal stage of diabetes mellitus. Vrachebnoe Delo 3: 46-49

Rüttermann, S.; Ritter, J.; Raab, W.H-M.; Bayer, R.; Janda, R., 2007: Laser-induced fluorescence to discriminate between a dental composite resin and tooth. Investigation of laser-induced fluorescence of an experimental pigment (Flu) to discriminate between a filling and the tooth and its influence on the material properties of experimental dental composites. Three experimental composites (EC) were ma...

Nagai Y.; Nagaoka A., 1992: Effects of sustained release dosage form of thyrotropin releasing hormone trh sr on the cerebral monoamine metabolism in rats and mice. Japanese Journal of Pharmacology 59(SUPPL 1): 95P

Werner, I.; Lodin, H., 1957: False Heller reaction due to roentgenographic contrast medium. Nordisk Medicin 57(8): 294-295

Cavalletti, B.; Rocchi, B., 2006: Efficiency grounds and welfare effects in decoupling farm support. Insights from an AGE model of the Italian economy. This paper investigates both efficiency and redistributive effects of the recent reform of Common Agricultural Policy in Italy. A general equilibrium model has been calibrated on a social accounting matrix of the Italian economy, adapted to repre...

Funk, D.J., 2016: Apneic oxygenation: Let's all just take a deep breath. Canadian Journal of Anaesthesia 64(4): 358-360

Medrano, J.V.; Andrés, Mía.Del.Mar.; García, Sía.; Herraiz, S.; Vilanova-Pérez, T.; Goossens, E.; Pellicer, A., 2017: Basic and Clinical Approaches for Fertility Preservation and Restoration in Cancer Patients. As gonadotoxic adverse effects of antineoplastic treatments can result in infertility, gamete cryopreservation is routinely offered to patients as the strategy to preserve their fertility. However, there are many cases where gold standards cannot...

Nesbitt Bruce E.; Muehlenbachs Karlis; Murowchick James B., 1989: Genetic implications of stable isotope characteristics of mesothermal Au deposits and related Sb and Hg deposits in the Canadian Cordillera. Economic Geology and the Bulletin of the Society of Economic Geologists 84(6): 1489-1506

Soenen, R., 1930: Two hitherto unpublished cases of bipartite malar bone from the Bonn Anatomisches Institut. Anat Anz 70(13/17): 320-324

Rebay G.; Messiga B., 2007: Prograde metamorphic evolution and development of chloritoid-bearing eclogitic assemblages in subcontinental metagabbro (Sesia-Lanzo Zone, Italy). In the coronitic metagabbroic rocks of the Corio and Monastero metagabbro bodies in the continental Sesia-Lanzo zone of the western Italian Alps, a variety of mineral reactions that testify to prograde conditions from greenschist to eclogite-facie...