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Visceral obesity as a risk factor for colorectal neoplasm


, : Visceral obesity as a risk factor for colorectal neoplasm. Journal of Gastroenterology and Hepatology 23(3): 411-417

Background and Aim: Obesity as a risk factor for colorectal neoplasm (CRN) is controversial. In the present study, we evaluated visceral obesity as a risk factor for CRN.Methods: We prospectively enrolled 200 consecutive, asymptomatic adults (male : female = 133:67, mean age, 50.9 +/- 8.5 years) undergoing both colonoscopy and abdominopelvic computed tomography (CT) scan for routine health evaluations. The presence or absence and the characteristics of CRN were determined during colonoscopy. The amount of visceral adipose tissue (VAT) and subcutaneous adipose tissue was measured by an abdominopelvic CT scan. Body mass index, waist circumference, and percentage of body fat were measured. Blood pressure and other blood markers for assessing the metabolic syndrome were also investigated.Results: Of the 200 patients, 53 (26.5%) had CRN. Old age, smoking, metabolic syndrome, and a high fasting plasma glucose level were associated with an increased risk of CRN. VAT (P < 0.01) and waist circumference (P = 0.01) were significantly higher in those with CRN. A multivariate analysis of the risks of CRN showed an odds ratio of 4.07 (95% confidence interval: 1.01-16.43, P = 0.03) for those with VAT over 136.61 cm(2) relative to those with VAT under 67.23 cm(2). Waist circumference, metabolic syndrome, and fasting plasma glucose levels were not independent risk factors for CRN in the multivariate analysis.Conclusion: Increased VAT is an independent risk factor for CRN. Further large scale studies are needed to clarify the causal relationship between VAT and CRN.

US$19.90

PMID: 17725596

DOI: 10.1111/j.1440-1746.2007.05125.x


Other references

O'Brien, G.M.; Criner, G.J., 1998: Surgery for severe COPD. Lung volume reduction and lung transplantation. A management strategy for patients with severe emphysema is shown in figure 2 on page 199. Although the reported physiologic improvements after LVRS are significantly less than those seen after lung transplantation, LVRS has the potential to impro...

Velićanski, A.S.; Cvetković, D.D.; Markov, Sša.L.; Šaponjac, V.T.Tumbas.; Vulić, J.J., 2014: Antioxidant and Antibacterial Activity of the Beverage Obtained by Fermentation of Sweetened Lemon Balm
(iMelissa officinalis L.) Tea with Symbiotic Consortium 
of Bacteria and Yeasts. NlmCategory="UNASSIGNED">Kombucha is a fermented tea beverage which is traditionally prepared by fermenting sweetened black or green tea (<i>Camellia sinensis</i> L.) with symbiotic consortium of bacteria and yeasts (SCOBY...

Anonymous, 1964: Pulp yields for various processes and wood species. Density, fiber length, and typical pulp yields, as obtained primarily by kraft and sulfite processes, are listed for many softwood and hardwood species grown in the United States.

Jeanjean, M.; Dehez-Delhaye, M.; Gommers, A., 1976: The effect of age on the in vitro insulin response in the rat part 2 glucose metabolism in epididymal adipose tissue. A decrease of the basal glucose metabolism with senescence in the isolated rat adipose tissue was demonstrated. In the presence of insulin, the oxidation of (U14C)-D-glucose and its incorporation into triglycerides are significantly increased at a...

Collado, R.; Fouz, B.; Sanjuán, E.; Amaro, C., 2001: Effectiveness of different vaccine formulations against vibriosis caused by Vibrio vulnificus serovar E (biotype 2) in European eels Anguilla anguilla. Vibriosis due to Vibrio vulnificus serovar E (biotype 2) is one of the main causes of mortality in European eels cultured in Europe. The main objective of this study was to develop a vaccine and a vaccination procedure against this pathogen. With...

Mazzoni, L.E.; Ellena, E.; Laksman, G.M.; Oliva, C., 1963: Herbicides in sunflower culture.. Chloramben at 4.5 kg, prometryne 1.5 kg and chlorpropham 9.46 kg in 180 1. water/ha gave good control of Chenopodium hircinum, Digitaria san. guinalis, Amaranthus hybridus and Echinochloa crus-galli when applied on the day after sowing sunflowers...

Merkov, A.M., 1957: Ways of development and basic achievements of Soviet sanitary statistics during the last 40 years. Sovetskoe Zdravookhranenie 16(10): 24-30

Romanini A.; Bertino J.R., 1990: Leucovorin effects on sequential methotrexate or timetrexate 5 fluorouracil cytotoxicity. Proceedings of the American Association for Cancer Research Annual Meeting 31: 389

Krismer, M., 2004: Comment to "Sagittal morphology and equilibrium of pelvis and spine" by G. Vaz et al. European Spine Journal 11(1): 88-88

Farney, R.J.; Walker, J.M.; Boyle, K.M.; Cloward, T.V.; Shilling, K.C., 2008: Adaptive servoventilation (ASV) in patients with sleep disordered breathing associated with chronic opioid medications for non-malignant pain. Adaptive servoventilation (ASV) can be effective therapy for specific types of central apnea such as Cheyne-Stokes respiration (CSR). Patients treated chronically with opioids develop central apneas and ataxic breathing patterns (Biot's respi...