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Phenotype and mRNA expression of syncytiotrophoblast microparticles isolated from human placenta


, : Phenotype and mRNA expression of syncytiotrophoblast microparticles isolated from human placenta. Annals of the New York Academy of Sciences 1137: 144-147

Fetal and neonatal alloimmune thromboctyopenia due to maternal human platelet antigen (HPA)-1a antibodies affects primigravidas. Immunization must occur early in pregnancy before fetal platelets enter maternal blood via fetomaternal hemorrhage. The HPA-1a antigen is located on platelet glycoprotein (GP)IIIa (CD61, beta3 integrin), which is also present on the placental syncytiotrophoblast (ST) and in direct contact with maternal blood.

US$19.90

PMID: 18837939

DOI: 10.1196/annals.1448.017


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