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Phenotype and mRNA expression of syncytiotrophoblast microparticles isolated from human placenta

, : Phenotype and mRNA expression of syncytiotrophoblast microparticles isolated from human placenta. Annals of the New York Academy of Sciences 1137: 144-147

Fetal and neonatal alloimmune thromboctyopenia due to maternal human platelet antigen (HPA)-1a antibodies affects primigravidas. Immunization must occur early in pregnancy before fetal platelets enter maternal blood via fetomaternal hemorrhage. The HPA-1a antigen is located on platelet glycoprotein (GP)IIIa (CD61, beta3 integrin), which is also present on the placental syncytiotrophoblast (ST) and in direct contact with maternal blood.


PMID: 18837939

DOI: 10.1196/annals.1448.017

Other references

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Eom, T-Yeon.; Bayazitov, I.T.; Anderson, K.; Yu, J.; Zakharenko, S.S., 2017: Schizophrenia-Related Microdeletion Impairs Emotional Memory through MicroRNA-Dependent Disruption of Thalamic Inputs to the Amygdala. Individuals with 22q11.2 deletion syndrome (22q11DS) are at high risk of developing psychiatric diseases such as schizophrenia. Individuals with 22q11DS and schizophrenia are impaired in emotional memory, anticipating, recalling, and assigning a...

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N.E.les; T.M.ulendyk, 2012: Ground-penetrating radar stratigraphy and depositional model for evolving Late Holocene aeolian dunes on the Lake Huron coast, Ontario. One of the largest (36<hsp sp="0.25"/>km<sup loc="post">2</sup>) Late Holocene systems anywhere in Ontario lies in Pinery Provincial Park on the southeast coast of Lake Huron and postdates a 12?km?long beach b...