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Pilot survey of aflatoxin-albumin adducts in sera from Egypt


, : Pilot survey of aflatoxin-albumin adducts in sera from Egypt. Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment 25(5): 583-587

Aflatoxins are potent liver carcinogens that frequently contaminate cereals in developing countries. Aflatoxin exposure has been predicted in Egypt but, to date, no studies have measured the level of aflatoxin-albumin (AF-alb) adducts as a validated biomarker to assess exposure. In this pilot survey, a limited number of sera samples, available from a hepatocellular carcinoma (HCC) case-control study in Egypt, were analysed. AF-alb was detected in 24/24 samples from HCC-negative individuals (geometric mean 9.0 pgmg(-1); range 3.5-25.8pg mg(-1)), while 7/22 samples from HCC-positive cases had detectable AF-alb (geometric mean 2.6 pg mg(-1); range: non-detectable-32.8 pg mg(-1)). These AF-alb data do not represent a case-control comparison due to inherent difficulties in comparing markers of dietary intake between controls and patients with disease. Although these data are limited, the potential health consequences of aflatoxin exposure in this region merit further investigation.

US$19.90

PMID: 18473213

DOI: 10.1080/02652030701713939


Other references

Reps, A.; Poznanski, S.; Smietana, Z., 1973: Biosynthesis of milk-coagulating proteases by the mould Byssochlamys fulva and Endothia parasitica. Byssochlamys fulva and Endothia parasitica were grown in a medium containing (%): NaNO3, 0.3; KH2PO4, 0.05; MgSO4.7H2O, 0.25; glucose, 1.0; dried wort, 1.0; and dried skim-milk, 0.5; to this medium had been added 0, 50, 100 or 200 mu g thiamin/l.,...

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Gittinger, J.P., 1967: Planning and agricultural policy in Iran-program effects and indirect effects. The thesis that planning activity may generate benefits which may persist though the plan is modified or abandoned is examined, with reference to Iranian planning efforts in the agricultural sector. Potential effects of planning are (1) " pro...

Yadav, B.S.; Ghoshal, S., 2009: Fungating scrotal mass: A rare clinical presentation of testicular tumor. A 20-year-old male patient presented with fungating scrotal mass. Investigations revealed yolk sac tumor with lung metastasis. The patient was treated with systemic chemotherapy. There was complete disappearance of the scrotal mass as well as meta...

Lehtola, S.; Jónsson, H., 2013: Unitary Optimization of Localized Molecular Orbitals. A unified formalism and its implementation is presented for Foster-Boys, fourth moment, Pipek-Mezey, and Edmiston-Ruedenberg type localization schemes of molecular orbitals through unitary optimization of the localizing transform matrix using a re...

Edwards, A.W.F., 2010: Statistical methods for evolutionary trees. In 1963 and 1964, L. L. Cavalli-Sforza and A. W. F. Edwards introduced novel methods for computing evolutionary trees from genetical data, initially for human populations from blood-group gene frequencies. The most important development was their...

Taylor, Iep, 1980: British Columbian plants in winter. Davidsonia er 11(4): 65-71

Astion, M.L.; Orkand, R.K., 1988: Electrogenic Na+/HCO3- cotransport in neuroglia. Membrane potential recording from glial cells in Necturus optic nerve in the presence of 2 mM Ba++, which was added to block the K+ conductance, gave the following results. 1) In HCO3- -free, low-Na+ solutions (11% of control; Na+ replaced with N-...

Hamburger, V., 1980: Trophic interactions in neurogenesis: a personal historical account. Using immunofluorescent and histopathological techniques, we studied the distribution and secretory activity of the glands of the larynx from 55 humans. The cavity of the larynx was covered with secretory glandular cells with the exception of the...

Burnasheva, D.V.; Shvalev, V.N.; Zabusov, G.I., 1975: Georgiĭ Ippolitovich Zabusov (on his 75th birthday). Arkhiv Anatomii, Gistologii i Embriologii 69(7): 115-117