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An epidemic of inoculation hepatitis

, : An epidemic of inoculation hepatitis. Ugeskrift for Laeger 116(17): 647-655

In 1952, 49 patients admitted to the Aarhus Kommunehospital with acute hepatitis were considered to be return cases, as against 6 to 7 return cases annually during immediately preceding years. The number of cases of acute hepatitis occurring during 1952 was relatively small. Age distribution of return cases showed a distinct difference from that of cases of acute epidemic hepatitis from the same district treated in the Marselisborg Hosp. On the other hand, age "distribution of return cases showed good agreement with that of the usual clinical material of the Medical Dept. Return cases were very frequent among patients treated with ACTH or cortisone and among diabetics, as compared with the usual material of the Dept. As the average minimum incubation period for return cases was 105 days, it was concluded that the hepatitis had been transmitted by inoculations. It seems likely that transmission of the virus took place during withdrawal of blood samples. During the same period, 2 cases of acute hepatitis occurred among the laboratory staff. On the basis of the frequency curve of the epidemic and contacts between the 2 laboratory technicians and the return cases, the possibility is considered that the source of infection can be traced to these 2 technicians.


PMID: 13169383

DOI: 10.1111/j.0954-6820.1954.tb18624.x

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