geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Bacterial factor in experimental hemorrhagic shock


, : Bacterial factor in experimental hemorrhagic shock. Amer Jour Physiol 179(3): 532-540

Dogs usually recover when transfused after exposure to hemorrhagic shock for 2 hours. If a mash made from normal dog liver is injected intraperitoneally into such dogs during shock they also recover. If the mash is made from liver from dogs in a terminal state of hemorrhagic shock, they die unless treated with penicillin, in which case most of them recover. Therefore, the liver from a dog in terminal hemorrhagic shock contains a lethal factor, which is not present in liver from a normal dog. This factor is a product of bacterial activity that develops as a result of the state of shock. Since this bacterial factor is fatal to a dog exposed to shock of only 2 hours duration, it will also be fatal to the dog in more prolonged shock from which it was obtained. Because the donor dog, like the recipient, recovers after transfusion if appropriately treated with penicillin or other antibiotics, there is a direct relationship between bacterial activity and irreversibility to transfusion in hemorrhagic shock. Most normal dogs recover when exposed to the bacterial factor in liver from a dog in terminal hemorrhagic shock. The failure of the dog in hemorrhagic shock to do so is attributable to the loss of the normal dog's capacity to inhibit bacterial activity. Impairment of this faculty develops within 2 hours after the onset of shock. Full recovery of this faculty in survivors from shock of short duration is not in evidence for at least 48 hours.

US$29.90


Other references

Powers, W.E., 1975: Teaching students to think. Respiratory Care 20(3): 280-282

Mandal, A.K.; Arguello, J.M., 2003: Role of metal binding domains in the Ag+-ATPase from Archaeoglobus fulgidus. Biophysical Journal 84(2 Part 2): 265a, February

Hayling Kiell L., 1993: The geoid and geophysical prospecting. Pages 299-319 1993

Hofmann, S.C.; Bruckner-Tuderman, L., 2006: Bullous pemphigoid: diagnostics and new therapeutic strategies. Bullous pemphigoid, the most frequent bullous autoimmune dermatosis of the adult, typically presents as disseminated tense blisters on normal or erythematous skin. The diagnosis can be confirmed by direct and indirect immunofluorescence, the detec...

Anonymous, 1969: Manganese minerals from Stanislawow (Lower Silesia) and their paragenesis. Lithiophorite-elisavetinskite and hollandite-psilomelane-type minerals, systematic descriptions, analytical data, Poland.

Seyahi, N.; Altiparmak, M.R.; Tascilar, K.; Pekpak, M.; Serdengecti, K.; Erek, E., 2007: Ultrasonographic maturation of native arteriovenous fistulae: a follow-up study. Background/aims. Ideal time needed for arteriovenous fistula (AVF) maturation is still. controversial. In this study, we aimed to investigate the natural course of AVF maturation and also investigated the factors affecting AVF maturation. Methods...

Gururaja, G.M.; Mundkinajeddu, D.; Dethe, S.M.; Sangli, G.K.; Abhilash, K.; Agarwal, A., 2014: Cholesterol esterase inhibitory activity of bioactives from leaves of Mangifera indica L. In the earlier studies, methanolic extract of Mangifera indica L leaf was exhibited hypocholesterol activity. However, the bioactive compounds responsible for the same are not reported so far. To isolate the bioactive compounds with hypocholestero...

Iglesias González, T.; Blanco-González, E.; Montes-Bayón, M., 2016: New strategy to address DNA-methyl transferase activity in ovarian cancer cell cultures by monitoring the formation of 5-methylcytosine using HPLC-UV. Methylation of mammalian genomic DNA is catalyzed by DNA methyltransferases (DNMTs). Aberrant expression and activity of these enzymes has been reported to play an important role in the initiation and progression of tumors and its response to chem...

Safavy, A.; Smith, D.C.; Bazooband, A.; Buchsbaum, D.J., 2002: Synthesis of the first diethylenetriaminepentahydroxamic acid (DTPH) bifunctional chelating agent. Synthesis of a new pentahydroxamic acid bifunctional chelating agent (BCA), constructed on the aminoazaalkyl core of diethylenetriaminepentaacetic acid (DTPA), is reported. Rational modifications in the structure of DTPA, which could result in an...

Wiersma P.A.; Dixon G.H., 1987: Histone h1e evidence that this h1 histone from trout erythrocytes is distinct from chicken h5. Federation Proceedings 46(6): 2170