+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Circulatory function in thyrotoxicosis and simple goiter

, : Circulatory function in thyrotoxicosis and simple goiter. Jour Osaka City Med Center 7(11): 1205-1229

A report is made of estimations of blood pressure, pulse rates and ecg on 39 patients with thyrotoxicosis and 31 patients with simple goiter, before and after Master's standard two-step test. Similar studies are repeated after the medication of mercaptoimidazole, radioactive iodine (I131) and desiccated thyroid. Labile high systolic and low diastolic blood pressure and definite tachycardia are found in many patients with thyrotoxicosis. After the exercise test, the time required for the pulse rate to regain a control level is prolonged in thyrotoxicosis, and this time proves to be a valuable index for evaluating cardiovascular conditions. Tachycardia or a slow recovery of pulse rates is also found in a few patients with simple goiter. Electrocardiographically, large Bazett's QT index which shows a normal value after exercise and is found in a quarter of the patients, a high incidence of negative, biphasic or notched T waves in right chest leads and the positive exercise test which is evidenced in about half the patients are emphasized in thyrotoxicosis. Another emphasis is given to high P, R and T waves with occasional flat T and rather frequently encountered ST depression (in 1/4 of the patients) and several kinds of arrhythmia. In simple goiter, almost all values are normal, though a few patients show flat T waves or positive two-step test. One month after the I131 treatment, those cases which show the positive exercise test increase in number and their cardiovascular reserve power decreases temporarily, but they show a gradual improvement. Mercaptoimidazole corrects tachycardia and heightens P and T waves. It lowers R waves and does not affect the exercise test. After the desiccated thyroid treatment in simple goiter, no large influences are observed of the cardiovascular system.


Other references

Baumgartner, R.N.; Roche, A.F.; Chumlea, W.C.; Siervogel, R.M.; Glueck, C.J., 1987: Fatness and fat patterns: associations with plasma lipids and blood pressures in adults, 18 to 57 years of age. As a part of the Fels Body Composition Study (an extension of the Fels Longitudinal Study in Yellow Springs, Ohio), the hypothesis was examined that a centripetal fat pattern, characterized by a greater proportion of trunkal than extremity adiposi...

Zander E.; Vizioli L., 1977: Cervical arachnoiditis due to toxocara canis report of 1 case. Acta Neurochirurgica 38(1/2): 145

Guo-Hong-Gang; Yang-Jian-Yi; Gao-Bao-Zhen; Han-Ning; Bian-Si-Cheng; Sa-Xiao-Ying, 2007: A study of single cell gel electrophoresis for detecting the DNA damage and repairing caused by acrylamide of two kinds of cells in mice. The DNA damage of two kinds of cells induced by acrylamide (AA)in mice were investigated using single cell gel electrophoresis, and the sensitivity to AA between reproductive cells and peripheral blood lymphocytes was compared. After kumning male...

Laura Mitrofan-Oprea; Marjo Jauhiainen; Jukka Pelkonen; Jukka Mönkkönen, 2008: Targeting of apoptotic pathways in cancer cells by zoledronic acid. Bone 42(supp-S1): 0

Walters, S.; Bhatt, N.; Medford, A.R.L., 2014: Reversible cerebellar signs due to sarcoid-related severe hypercalcaemia. Qjm 106(7): 667-669

Dillon W.P.; Knebel H.J.; Wood S.A.; Aubrey D.G., 1979: Erosional channels on a beach shoreface. Abstracts with Programs - Geological Society of America 11(7): 413

Fan, Q.; Zhang, C.; Shokat, K.; William, W.A., 2002: Selective inhibition of a transforming receptor tyrosine kinase reveals dependence on aberrant oncogenic signaling. Proceedings of the American Association for Cancer Research Annual Meeting 43: 724, March

Azumi, M.; Kobayashi, H.; Aoki, N.; Sato, K.; Kimura, S.; Kakizaki, H.; Tateno, M., 2010: Six-transmembrane epithelial antigen of the prostate as an immunotherapeutic target for renal cell and bladder cancer. T-cell based immunotherapy for renal cell and bladder cancer is one of the most promising therapeutic approaches. STEAP is a novel cell surface protein that is over expressed in various cancers, including renal cell and bladder cancer. Recently we...

Russell, T.R., 2009: Financial and lifestyle rewards associated with subspecialization. Bulletin of the American College of Surgeons 93(10): 4-5

Larsson, C., 1978: The renal prostaglandin system: localization and some biological effects. The renal prostaglandins (PGs) are formed mainly in the endoplasmatic reticulum from locally available precursor, arachidonic acid (C20:4). Although the main PG formation occurs in the papilla, significant amounts of PGs are also formed in the cor...