+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Comparative activity of isologous versus homologous mouse bone marrow on lymphoid tumor production following irradiation

, : Comparative activity of isologous versus homologous mouse bone marrow on lymphoid tumor production following irradiation. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine 98(2): 384-387

Lymphoid tumor development in irradiated C57BL mice was specifically inhibited by isologous marrow; homologous marrow, including F1 hybrid marrow, did not inhibit the tumor process in C57BL mice after sublethal radiation exposures. F1 (C57BL x BALB) hybrid mice were protected against radiation-induced lymphomas by compatible marrow. Protection was essentially equal, whether the marrow injected was from F1 hybrids or either parental strain. The similarity between these results and those previously reported with respect to marrow-mediated thymic weight regeneration is discussed. Since host immune reactions to incompatible cells are not abolished at these radiation dose levels, it is inferred that these marrow injection effects require the persistent presence of viable marrow cells. A number of lymphomas were tested for transplantibility into various strains. Of those tested, none arising in C57BL mice injected with homologous marrow were other than C57BL tumors, whereas 3 of 9 tumors which arose in F1 hybrids despite marrow injections, grew in the parental marrow donor strain, indicating that repopulation must have occurred in these cases at least.


PMID: 13554653

DOI: 10.3181/00379727-98-24051

Other references

Límanová, Z.; Neuwirtová, R.; Procházková, M., 1988: Aspiration biopsy of the thyroid in endocrinology practice. Casopis Lekaru Ceskych 127(6): 174-177

Agenjo R., 1972: Cleoceris viminalis new record new genus and species for the iberian peninsula lepidoptera noctuidae. EOS-Revista Espanola de Entomologia 48(1-4): 7-10

Samsonov, V.A., 1995: Carcinoid lung tumors: clinico-morphologic characteristics, diagnosis. Review of the literature on carcinoid lung tumors covers classification, macro- and microscopical structure, prognosis of typical and atypical carcinoids, role of special staining methods and electron microscopy in their diagnosis. The role of ele...

Reiches, A.J., 1953: Angular stomatitis treated with silicote ointment. A.M.A. Archives of Dermatology and Syphilology 68(3): 336-337

Anonymous, 1978: Myths of vitamins. Leaflet L Texas Agricultural Extension Service: 78 (1569)

Jankov P.; Apfelbach R., 1981: Age dependent learning speed of female laboratory rats. The learning speed of female laboratory rats was studied between 32 and 500 days of age. The animals had to distinguish between 2 different visual signs. Learning speed was highest between days 52 and 58 and again between days 72 and 172. In very...

Salado, E.E.; Resconi, V.C., 2007: Replacement of sorghum silage by corn grain in feedlot. 3. Sensory evaluation. Revista Argentina de Produccion Animal 27(Suppl.1): 384-385

Anonymous, 2002: Enthusiasm and youth shines at Great Gransden centenary. Poultry World 156(11

Plaisier, C.; Cok, A.; Scott, J.; Opejin, A.; Bushhouse, K.T.; Salie, M.J.; Louters, L.L., 2011: Effects of cinnamaldehyde on the glucose transport activity of GLUT1. There is accumulating evidence that cinnamon extracts contain components that enhance insulin action. However, little is know about the effects of cinnamon on non-insulin stimulated glucose uptake. Therefore, the effects of cinnamaldehyde on the g...

Kiew, P.Loo.; Don, M.Mat., 2012: Jewel of the seabed: sea cucumbers as nutritional and drug candidates. Marine sources have been attracting the attention of scientists and manufacturers worldwide hoping to find new alternatives for biological active substances. Promising new research indicates that sea cucumber, which is slug-like in appearance and...