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Discontinuous decay of the action potential of the rat gastrocnemius as recorded from an intracellular location


, : Discontinuous decay of the action potential of the rat gastrocnemius as recorded from an intracellular location. Journal of Cellular Physiology 65(2): 255-260

Fractionation of intracellular action potential has been observed, with (1) an initial graded decline of amplitude and appearance of a notch; (2) a progressive delay and eventual disappearance of a component, with stepwise decrease in area, and (3) the occasional sequential disappearance of as many as three components of the same order of magnitude in area and amplitude. The possibilities of block, movement, or extracellularly recorded responses as cause for these physiological "quanta" have been reviewed. One possible hypothesis is the existence of "patches" of membrane with independent characteristics of excitability and responsivity, which become manifest as a result of damage inflected by the electrode.

US$19.90

PMID: 5834563

DOI: 10.1002/jcp.1030650213


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