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Drugs, Shock Intensity, And The Cer

, : Drugs, Shock Intensity, And The Cer. Psychopharmacologia 4: 148-153

The effects of chronic small doses of reserpine (0.2 mg./kg.) and of chlorpromazine (1.5 mg./kg.) upon the CER were studied using albino rats as subjects. It was found that reserpine reliably reduced the CER at a relatively low shock intensity (0.8 ma.) but, with a more severe shock (1.0 ma.), the results were equivocal. Chlorpromazine inhibited the CER at 1.0 ma. At the dosage and time parameters studied, chlorpromazine induced less depression of VI rate than did reserpine; recovery from reserpine effects was generally more gradual than was recovery from chronic chlorpromazine treatment.


PMID: 14050420

DOI: 10.1007/bf00413332

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