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Effect of stimulation of the chemoreceptors of the intestine on some indices of brain circulation Data from the scientific conference on the physiology and pathology of the corticovisceral interrelations and functional systems of the organism


, : Effect of stimulation of the chemoreceptors of the intestine on some indices of brain circulation Data from the scientific conference on the physiology and pathology of the corticovisceral interrelations and functional systems of the organism. Effect of stimulation of the chemoreceptors of the intestine on some indices of brain circulation Data from the scientific conference on the physiology and pathology of the corticovisceral interrelations and functional systems of the organism [2] Vliyanie razdrazheniya khemoretseptorov sosudov kishechnika na nekotorye pokazateli mozgovogo krovoobrash-cheniya In: Materialy Nauchnoi konferentsiipo problemam "Fiziologiya i patologiya kortiko-vistseral'nykh vzaimootnoshenii i funktsional&a

The arterial pressure, pressure in the circle of Willis, venous pressure, and in part of the experiments, the intracranial pres-pressure was recorded from dogs. A section of the small intestine 13 to 18 cm in length, 10 to 18 cm from the site where the caecum joins the small intestine, was isolated from the general circulation but nerve connections were preserved; it was perfused with an oxygenated Tyrode's solution at 36.5 to 37[degree]C. The drugs being studied were introduced into the perfusion solution. When acetylcholine, choline, and ephedrine were injected, in 55.1% of the cases, a pressor reaction was noted on the part of the arterial pressure and Willis' circle pressure; in 29.5% of the cases a depressor reaction was noted. In isolated instances an extremely varied reaction was observed. A characteristic feature of the reflex reactions under observation was the absence of parallelism between the indices of general arterial pressure and the pressure in the vessels of Willis' circle. The magnitude of the changes in the total arterial pressure exceeded that in the Willis' circle pressure. The jugular vein pressure underwent parallel changes with the pressure in Willis' circle. The intracranial pressure did not change. After denervation of the section of the intestine undergoing perfusion or when a procaine solution was injected into it, the changes in pressure disappeared indicating the reflex nature of the reactions observed.

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