+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Electrocardiographic changes and concentration of magnesium in serum following intravenous injection of magnesium salts

, : Electrocardiographic changes and concentration of magnesium in serum following intravenous injection of magnesium salts. Amer Jour Physiol 126(3): 720-730

Isotonic magnesium sulfate was given to unanesthetized dogs by continuous intraven. inj. Frequent electrocardiograms and blood samples were taken for analysis of the magnesium in the serum. The heart rate immediately increased as the conc. of Mg in the serum rose from 2 to 5 mEq. per liter. This was soon followed by a bradycardia. Intracardiac conduction was depressed as seen from (1) progressive increase in P-R interval beginning at 5 to 10 mEq. magnesium per liter of serum and continuing till death, (2) occasional S-A and A-V block of various grades, occurring at levels greater than 15 mEq. per liter, (3) widening of QRS complex indicating an increase in intraventricular conduction time, beginning at 5 to 10 mEq. per liter. Natural respiration disappeared at 17 to 27 mEq. per liter. Occasionally cardiac arrest occurred simultaneously, but never preceded respiratory arrest; more often under artificial respiration the heart continued to beat until a much higher conc. of Mg was attained. Cardiac arrest appeared over a wide range, 17 to 66 mEq. per liter, but most frequently at 27 to 44 mEq. per liter. Normal systole was maintained till the end. Inj. of Mg in cats produced a sequence of changes similar to that observed in dogs.


Other references

L'Hermite, J.; Colombel, P.; Coudane, H., 1977: Prostatic cryotherapy apropos of 200 freezings. Journal D'urologie et de Nephrologie 83 Suppl 2: 381-385

Kümmerli, R.; Gardner, A.; West, S.A.; Griffin, A.S., 2009: Limited dispersal, budding dispersal, and cooperation: an experimental study. Numerous theoretical studies have investigated how limited dispersal may provide an explanation for the evolution of cooperation, by leading to interactions between relatives. However, despite considerable theoretical attention, there has been a l...

Mutzbauer, T.S.; Munz, R.; Helm, M.; Lampl, L.A.; Herrmann, M., 2003: Emergency cricothyrotomy--puncture or anatomical preparation? Peculiarities of two methods for emergency airway access demonstrated in a cadaver model. The aim of the study was a demonstration of peculiarities of two invasive airway management methods performed by anesthesiology residents as a subgroup of emergency physicians. During an airway management training seminar,2 groups including 18 ana...

Favrot, J.-C., 1969: Soil map of France: 1/100 000. Vichy. Sheet L15. Explanatory notes. Sixty-two mapping units representing raw mineral soils, weakly developed soils, vertisols, andosols, calcimorphic soils, isohumic soils, brown soils and hydromorphic soils are described and their agricultural potential is indicated.

Ross Nancy, 1992: Lattice vibration and mineral stability. The Mineralogical Society Series 3: 132-169

Wegert Frank, 1961: Zur Definition und Klassifizierung einiger erdoelgeologischer Begriffe. Some essential terms for the loci of petroleum deposits are discussed and defined on the basis of terms and definitions which have been proposed in the Russian literature, as a contribution toward clarification and standardization of the German no...

Bar, M.; Biederman, I., 1998: Evidence that representations mediating subliminal visual priming are localized in an intermediate cortical area such as V4. IOVS 39(4): S1113, March 15

Powell D.A.; Levine D.; James L., 1986: Parasagittal knife cuts that interrupt sublenticular and posterior internal capsule impair cardiac conditioning but have no effect on concomitant eyeblink conditioning. Society for Neuroscience Abstracts 12(2): 752

Kenny, A.D., 1966: Hypercalciuric response to acute parathyroidectomy in rats: effects of adrenalectomy. Endocrinology 78(4): 880-883

Janoir, C.; Grénery, J.; Savariau-Lacomme, M-P.; Collignon, A., 2004: Characterization of an extracellular protease from Clostridium difficile. Clostridium difficile is an intestinal pathogen, which produces two main virulence factors, the exotoxins A and B. Other bacterial structures have been implicated in the colonization of the gastrointestinal tract, which is the first step of the pa...