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Embryonic Mortality In Mouse Populations After Eleven Generations Of Spermatogonial Irradiation

, : Embryonic Mortality In Mouse Populations After Eleven Generations Of Spermatogonial Irradiation. Genetics 50: Suppl:1053-63

Males of 6 populations of "inbred" mice and of 6 populations of "hybrid" mice were mated with their sisters and with females of an unrelated inbred stain. The 6 populations in each group represent 3 levels of spermatog-onial X-irradiation and 2 levels of inbreeding. Spermatogonia were exposed to 0, 50, or 100 r of X-rays in each generation, and the inbreed-ing coefficient was varied but controlled within limits by fixing the number of mated pairs per generation as either 8 or 16. The popula-tions were propagated for 11 generations with random mating excluding brother-sister matings. The females, both sister and unrelated, were killed at about 15 days of pregnancy and the numbers of corpora lutea, "moles," dead fetuses, and living fetuses counted to see if any differences in embryonic mortility attributable to radiation exposure, inbreeding level, or both had developed between the populations. The mice in the litters from the brother-sister matings each received 2 irradiated or control genomes, whereas the mice in the litters from the outcrosses received only one irradiated or control genome. No differences between the populations related to radiation or inbreeding experiences were apparent in rates of embryonic losses prior to implantation, immediately after implantation, or long after implantation. The total number of females dissected was 902; the average number was 37.6 per set.


PMID: 14234697

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Shen, Q.W.; Swartz, D.R., 2010: Influence of salt and pyrophosphate on bovine fast and slow myosin S1 dissociation from actin. The kinetics of myosin dissociation from actin was investigated and also the impact of salt, MgPPi, and myosin heavy chain isoform on myosin subfragment 1 (S1) dissociation from actin using purified proteins and fluorescence spectroscopy. Both NaC...

Chavalittamrong, B.; Chearskul, S.; Tuchinda, M., 1986: Protective value of BCG vaccination in children in Bangkok, Thailand. The protective effect of bacille Calmette-Guérin (BCG) vaccination against tuberculosis is controversial. In a study, 330 patients less than 12 years of age with tuberculosis, 52.1% of whom had had BCG vaccination, were compared with a control gr...

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Al' smik, P.I., 1969: Potato breeding in Belorussia. The main methods of breeding and the characteristics of the main varieties bred are described in this book.

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Hauswirth, A.W.; Florian, S.; Krauth, M.T.; Printz, D.; Fritsch, G.; Sotlar, K.; Schernthaner, G.H.; Wacheck, V.; Selzer, E.; Sperr, W.R.; Valent, P., 2003: Expression of the target receptor CD33 on CD34+/CD38-/CD123+ AML stem cells. The cell surface antigen CD33/Siglec-3 is becoming increasingly important as target of antibody-mediated therapy in AML. In normal myelopoiesis, expression of CD33 is restricted to advanced stages of differentiation, whereas primitive stem cells d...

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Linas S.L.; Anderson R.J.; Guggenheim S.; Dickmann D.; Robertson G.; Berl T., 1979: Mechanism of impaired water excretion in cirrhosis. Kidney International 16(6): 873

Youssef, K.A., 1982: Instant culture media and method of sterilizing same. It is claimed that the disadvantages of sterilizing culture media in laboratories by autoclaving may be overcome by adding to the nutrient media up to 5% of a gelling agent, 0.015-0.03% of a bleaching agent with bactericidal and biocidal propertie...