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Evidence of the occurrence of a large RNA molecule per ribonucleo-protein particle

, : Evidence of the occurrence of a large RNA molecule per ribonucleo-protein particle. Biochim Et Biophys Acta 37(2): 238-242

A purified ribose nucleic acid (RNA) preparation consisting of two sedimenting components has been obtained from mouse brains. The molecular weights of these two components, as determined from the sedimentation and viscosity data, are 1.7x106 and 0.7x106, respectively. The larger value is equal to the RNA content of one mole of the larger tissue ribonucleoprotein. This result supports the previously advanced hypothesis that one RNA particle with a molecular weight of about 1.7x106 is contained in one molecule of a certain class of ribonucleoprotein particle.


PMID: 13809617

DOI: 10.1016/0006-3002(60)90229-8

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