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Grid Shock Test For Analgesic Assay In Mice

, : Grid Shock Test For Analgesic Assay In Mice. Medicina Experimentalis 9: 146-150

An assay for the evaluation of weak and strong analgesics is described. It is based on the determination of the elevation of the current threshold which produces nociceptive stimulation in freely moving mice receiving an electric shock to their paws. Weak analgesics of the acelylsalicylic acid type can be uncovered by this method using non-toxic doses.


PMID: 14083334

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