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Harvard Med


, : Harvard Med. Sch Boston] Comparative Susceptibility Of Roller Tube Cultures Of Different Tissues to Poliomyelitis Viruses Ann New York Acad Sci 61(4): 822-829

During an investigation of the roller-tube tissue culture as applied to the isolation of poliomyelitis viruses from human feces, it became apparent that the tissues tested varied in their capacity to reveal these agents when the latter were present in low concentration. This observation led not only to a study of the comparative sensitivity of certain of the tissues, but also to the development of techniques that resulted in a higher incidence of recovery of virus. Data illustrative of these variations in tissue sensitivity are presented in this paper, and certain of their implications are considered.

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