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Healing of bronchial wounds following pulmonary resection

, : Healing of bronchial wounds following pulmonary resection. Surgery, Gynecology & Obstetrics 110: 35-43

Bronchial wound closures were studied grossly and microscopically after pneumonectomies on 40 dogs. In contrast to closures with epithelial surface approximation, layer-to-layer closures initiated earlier regeneration of thick differentiated columnar epithelium and rapid healing in the subepithelial layer. When nonabsorbable silk sutures extended through the mucosa into the lumen, as in epithelial closures, chronic reaction and ulceration resulted. This result was eliminated in the layer-to-layer closures by extramucosal suturing. This layer approximation also eliminated residual bronchial stumps with blind pouches by allowing shorter amputation of bronchi. In one method of layer closures, with amputation of the bronchi at the tracheo-bronchial junction, absorbable catgut sutures were successfully used to minimize stress on the extramucosal nonabsorbable sutures.


PMID: 14400530

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