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Incidence of infarcts of the brain in heart disease

, : Incidence of infarcts of the brain in heart disease. J Pathol Bacteriol 88(2): 463-470

A definition and method of counting arterial infarcts in the brain are described. Twelve per cent of 100 patients without heart disease and 53.8% of 340 with heart disease showed cerebral infarction. The incidence was much the same in most types of heart disease, though bacterial endocarditis showed an exceptionally high incidence. Heart disease complicated by atrial fibrillation, mural thrombus in the left side of the heart or congestive cardiac failure showed no higher incidence. A small subgroup with both atrial fibrillation and old myocardial infarction was an exception and showed a higher incidence. Occlusions of arteries to the brain were demonstrated in only 24 of the 340 patients with heart disease. We prefer embolism from thrombus formed in the heart as an explanation for the majority of these infarcts. Of 440 brains examined, 5 showed multiple sclerosis.


PMID: 14226418

DOI: 10.1002/path.1700880209

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