+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

On the metabolic equivalence of deuterium and tritium in animal experimentation

, : On the metabolic equivalence of deuterium and tritium in animal experimentation. Archives of Biochemistry and Biophysics 42(1): 219-220

Four rats were injd. intraperit. with sufficient D2O (92.5%) to bring the concn. in body water to approx. 5%. The injd. soln. also contained 0.9% NaCl and approx. 1 mc./ml. HTO. Two additional injns. of half the original quantity were given at 3.5-day intervals. 3 days after the last injns. the animals were sacrificed. The retention ratios were very close to unity, indicating similar metabolic behavior of deuterium-labelled and tritium-labelled compounds.


PMID: 13031625

DOI: 10.1016/0003-9861(53)90255-0

Other references

Mik, J., 1886: Die Dipteren-Genera Paolo Lioy's. Mik considers Lioy's work to have been quite without value, and occupies these pages with a synonymy of his genera. This I have not reproduced in our "systematic" part.

Heggers, J.P.; Kucukcelebi, A.; Listengarten, D.; Stabenau, J.; Ko, F.; Broemeling, L.D.; Robson, M.C.; Winters, W.D., 1996: Beneficial effect of Aloe on wound healing in an excisional wound model. Recent evidence from in vitro and in vivo experiments suggests that topical antimicrobials may be toxic to fibroblasts and keratinocytes and retard wound healing. The purpose of this study was to determine the effects of Aloe, a potential wound-he...

Nonogi, H.; Hess, O.M.; Ritter, M.; Bortone, A.; Corin, W.J.; Grimm, J.; Krayenbuehl, H.P., 1988: Prevention of coronary vasoconstriction by diltiazem during dynamic exercise in patients with coronary artery disease. Whether exercise-induced vasoconstriction of coronary artery stenoses is modified by the administration of calcium antagonists was examined in 14 patients with classic angina pectoris. In this group the effect of intracoronary diltiazem (2 to 3 mg...

Stehr, K.; Hickl, E.; Schelle, H., 1965: Studies On The Prenatal Blood Sugar Level In Mother And Child. Monatsschrift für Kinderheilkunde 113: 294-296

Claudio, J.O.; Malo, D.; Rouleau, G.A., 1994: Confirmation of the synteny between human chromosome 22 and mouse chromosome 11 regions carrying the neurofibromatosis type 2 gene. American Journal of Human Genetics 55(3 SUPPL ): A182

Anand, L.R., 1989: Biology of mesidionema narayani new species mesidionematidae drilonematoidea an earthworm nematode from hyderabad a.p. Mesidionema narayani sp. n. (Mesidionematidae : Drilonematoidea) was described from earthworms in Hyderabad, Andhra Pradesh (India). The new species differs from other species of the genus in the location of excretory pore, number of anal papillae...

Gordon, J., 1963: State farms in Ghana. A discussion of Ghana's programme for establishing mechanized state farms. Nearly one hundred such farms had been started by March 1963. The crops grown include rubber, oil palms, bananas and citrus. Some 800 hectares or more will be cropped...

Elçin, Y.M., 1995: Control of mosquito larvae by encapsulated pathogen Bacillus thuringiensis var. israelensis. Bacillus thuringiensis var. israelensis (B.t.i.) containing alginate microcapsules were prepared in order to maintain durable formulations which could resist several effects causing reduced efficiency during applications. B.t.i. spores were harves...

Anonymous, 1978: Better skimming efficiency claim for new unit. The new Alfa-Laval self-cleaning hermetic separator and its operation are briefly described. The desludging is effected by a hydraulically-operated sliding bowl bottom which is lowered momentarily to expose openings through which the sludge is eje...

Miki, E.; Lee, E.T.; Lee, S.C.; Wang, Y.; Keen, H., 2001: Development of a computer-assisted retinal image analysis system using telemedical approach. IOVS 42(4): S808, March 15