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Oxidation Of Extramitochondrial Diphosphopyridine Nucleotide By Various Tissues Of The Mouse

, : Oxidation Of Extramitochondrial Diphosphopyridine Nucleotide By Various Tissues Of The Mouse. Science 145(3632): 606-607

Exogenous reduced diphosphopyridine nucleotide was not oxidized by mitochondria but by cytoplasmic hydrogen-accepting systems catalyzed by lactic, alpha-glycerophosphate, and malic dehydrogenases. The three enzymes were found in all tissues of the mouse; the amount of activity of each enzyme differed in the various tissues, however. It is suggested that each tissue has a unique pattern for oxidation of extramitochondrial diphosphopyridine nucleotide.


PMID: 14163795

DOI: 10.1126/science.145.3632.606

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