+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Progressive Changes In Cardiovascular Function After Unilateral Heart Irradiation

, : Progressive Changes In Cardiovascular Function After Unilateral Heart Irradiation. American Journal of Physiology 206: 289-293

Chronic heart failure was produced by giving 20,000 r Co60 irradiation to either the right or left ventricle in nine closed-chest animals. Measurements of right and left atrial pressures, arterial pressure, pulse rate, body weight, and blood volume were made before and after irradiation. The right and left atrial pressures rose progressively until death in three animals irradiated on the right side. In six animals irradiated on the left side, the left atrial pressure rose progressively, but the right atrial pressure either did not rise or rose only during the latter stages of failure. Declining arterial pressure and increasing pulse rate were common to both groups. Increases in blood volume were observed in all animals, but this increase was only significant in the group irradiated on the left side. At autopsy, 70-100% of the right ventricular muscle was damaged in dogs irradiated on the right side, and 40-70% of the left ventricle in dogs irradiated on the left side. Hydrothorax and liver congestion were found in the right-sided group and pulmonary congestion in the left-sided group.


PMID: 14120428

Other references

Chalecka Franaszek, E.; Dikshit, M.; Nalepa, I.; Vetulani, J., 1992: Effect of centpropazine, a new antidepressant, on adrenergic receptor response. Polish Journal of Pharmacology & Pharmacy 44(SUPPL ): 108

Mi, R.R., 1985: Serum lactic dehydrogenase assay in the diagnosis and therapeutic monitored of ovarian carcinoma. Zhonghua Fu Chan Ke Za Zhi 20(2): 81-4, 126

Tardea, A.T.rdea, C.O.taciuc, I., 1983: Directions for vine growing in the form of bilateral cordon and the influence of this cordon on the biological characteristics of the productive potentialities. Analele stiintifice ale Universitatii "Al I Cuza" din Iasi Sectiunea 2 a: Biologie9(29): 45-46

Van Schooten, F.J.; Maas, L.; Moonen, E.; Kleinjans, J.; Van Der Oost, R., 1993: Biotransformation and formation of DNA adducts in feral eel and rats exposed to polycyclic aromatic hydrocarbon contaminated sediments. Proceedings of the American Association for Cancer Research Annual Meeting 34(0): 156

Mercado, D.Fabio.; Magnacca, G.; Malandrino, M.; Rubert, A.; Montoneri, E.; Celi, L.; Bianco Prevot, A.; Gonzalez, Mónica.C., 2014: Paramagnetic iron-doped hydroxyapatite nanoparticles with improved metal sorption properties. A bioorganic substrates-mediated synthesis. This paper describes the synthesis of paramegnetic iron-containing hydroxyapatite nanoparticles and their increased Cu(2+) sorbent capacity when using Ca(2+) complexes of soluble bioorganic substrates from urban wastes as synthesis precursors. A t...

Hatterer, E.; Shang, L.; Simonet, P.; Herren, S.; Daubeuf, B.; Teixeira, Séphanie.; Reilly, J.; Elson, G.; Nelson, R.; Gabay, C.; Sokolove, J.; McInnes, I.B.; Kosco-Vilbois, M.; Ferlin, W.; Monnet, E.; D.M.n, C., 2016: A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated disease. Increased expression of toll-like receptor 4 (TLR4) and its endogenous ligands, is characteristic of rheumatoid arthritis (RA) synovitis. In this study, we evaluated how these TLR4 ligands may drive pathogenic processes and whether the fine profil...

Wilson, R.E.; Keng, P.C.; Sutherland, R.M., 1990: Changes in growth characteristics and macromolecular synthesis on recovery from severe hypoxia. Chinese hamster ovary cells subjected to severe hypoxia stop growing. When oxygen was reintroduced growth resumed, but at a slower rate. The longer the hypoxic stress, the slower the recovery growth rate. Six hours of hypoxia caused very little de...

Raveche E.S.; Klassen L.; Steinberg A.D., 1977: Sex differences in the formation of anti thymus derived cell antibodies. Arthritis & Rheumatism 20(1): 132

Bell M.R.; Kaufmann U.P.; Vlietstra R.E.; Holmes D.R.Jr, 1990: Combined percutaneous coronary atherectomy and coronary angioplasty experience in 19 consecutive patients. Among 82 patients undergoing coronary atherectomy, 19 (23%) underwent this procedure in combination with coronary angioplasty. The most frequently involved vessel was the left anterior descending coronary artery. In 11 patients (58%), attempted ar...

Wei, T.; Xiong, F-fei.; Wang, S-dong.; Wang, K.; Zhang, Y-yu.; Zhang, Q-hua., 2015: Flavonoid ingredients of Ginkgo biloba leaf extract regulate lipid metabolism through Sp1-mediated carnitine palmitoyltranferase 1A up-regulation. Lipid accumulation is the primary evidence of non-alcoholic fatty liver disease (NAFLD). Ginkgo biloba extract (GBE) and its flavonoid ingredients (quercetin, kaempferol, and isorhamnetin) could lessen the lipid accumulation associated with up-reg...