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Technique for the preservation of tetracycline fluorescence in ascites tumor cells

, : Technique for the preservation of tetracycline fluorescence in ascites tumor cells. Journal of Pharmaceutical Sciences 56(2): 272-274

Fluorescence microscopy has a potential application in cellular pharmacology for the study of intra- and intercellular distribution of pharmacological agents. A method is reported for preparing permanent preparations of tetracycline-retaining ascite tumor cells. A combination of glutaral-dehyde fixation followed by glycerol dehydration was found satisfactory.


PMID: 5337946

DOI: 10.1002/jps.2600560226

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