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The effect of whole skeletal muscle on blood sugar in vitro


, : The effect of whole skeletal muscle on blood sugar in vitro. Jour Biol Chem 83(1): 129-136

When normal skeletal muscle, rich in glycogen, is incubated with blood, the decrease in blood sugar at the end of the 3rd hr. is as small as when blood is incubated alone. On the other hand, when deglyco-genated muscle of epinephrinized animals is used there is a marked drop in the sugar content of the blood. It seems, therefore, that deglycogenated muscle has the power of utilizing glucose in vitro, but it is not possible to state whether the glucose that disappears is burned or changed into glycogen.

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