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The histopathology of the macroglobulinemia-of Waldenstrom


, : The histopathology of the macroglobulinemia-of Waldenstrom. Jour Natl Cancer Inst 22(5): 887-917

The histopathologic, phase microscopic, and clinical pathologic features of macroglobulinemia are described. The presence of lymphoid plasma cells containing intranuclear periodic acid-Schiff positive material is noted in 2 cases with the macroglobulinemia of Waldenstrom and in 1 with the Bing-Neel syndrome. It is suggested that this material and the intranuclear "vacuoles" observed in phase microscopy are chemically identical to the circulating 18S, hexose-richy-macroglobulin. The classification of the macroglobulinemia of Waldenstrom as a neoplasm of reticuloendothelial origin is mentioned and the differentiation between this disease, lymphoma, and multiple myeloma is discussed.

US$29.90

PMID: 13655069


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