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The preparation of human immune serum for the treatment of poliomyelitis

, : The preparation of human immune serum for the treatment of poliomyelitis. MED JOUR AUSTRALIA 18(Vol 1, No 9): 251-254

A tourniquet was applied to the arm of the donor, and a small area of the skin over the vein was then frozen with ethyl chloride and the needle passed into the vein. The average amount of blood drawn was 416 cc. Blood was incubated for 1 hr. at 37[degree] C, then stored at 6-8[degree] for 4-5 days. The serum was then filtered through a Seitz filter, and sealed in an ampoule. At no time from plunging of needle into vein to sealing of ampoule was the blood exposed to air. The age range of the donors was 5-40 yrs.; *60% were 8-20 yrs. old. The serum % from the blood was 38.2 in one campaign, and 37.7 in another.


Other references

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Alam, M.; Zhestkov, V.; Sani, B., P.; Venepally, P.; Levin, A., A.; Kazmer, S.; Li, E.; Norris, A., W.; Zhang, X.-Kun; Lee, M.-Ock; Hill, D., L.; Lin, T.-Han; Brouillette, W., J.; Muccio, D., D., 1995: Conformationally defined 6-s-trans-retinoic acid analogs. 2. Selective agonists for nuclear receptor binding and transcriptional activity. We recently demonstrated in animal models that a new conformationally defined RA isomer (Vaezi et al. J. Med. Chem. 1994, 37, 4499-4507) was as effective as RA in the prevention of skin papillomas but was less toxic. In order to provide more detai...

Osier, F.H.A.; Murungi, L.M.; Fegan, G.; Tuju, J.; Tetteh, K.K.; Bull, P.C.; Conway, D.J.; Marsh, K., 2010: Allele-specific antibodies to Plasmodium falciparum merozoite surface protein-2 and protection against clinical malaria. IgG and IgG3 antibodies to merozoite surface protein-2 (MSP-2) of <i>Plasmodium falciparum</i> have been associated with protection from clinical malaria in independent studies. We determined whether this protection was allele-specific...

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Ramírez-Molina, J.Luis.; Di Giacomo, R.; Mariani, V.; Deleo, F.; Cardinale, F.; Uscátegui-Daccarett, Aélica.María.; Lorenzana, P.; Tassi, L., 2017: Surgical outcomes in two different age groups with Focal Cortical Dysplasia type II: Any real difference?. Focal Cortical Dysplasias (FCDs) represent a common architectural cortical disorder underlying drug-resistant focal epilepsy. So far, studies aimed at evaluating whether age at surgery is a factor influencing surgical outcome are lacking, so that...

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Uysal, H.; Bahşi, Y.Z.; Yurdakul, M., 1999: Babinski reflex by sural stimulation and dysfunction of descending motor pathway. The aim of the study was to find out the relationship between the Babinski reflex and flexor polysynaptic reflexes which was evaluated by sural nerve stimulation, and to evaluate the descending motor pathway in involvement by cervical and transcor...