+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Transformation of African green monkey kidney cells by irradiated adenovirus 7-simian virus 40 hybrid

, : Transformation of African green monkey kidney cells by irradiated adenovirus 7-simian virus 40 hybrid. Journal of Virology 2(3): 173-177

The ability of adenovirus 7-simian virus 40 (SV40) hybrid (strain LL "E-46") to replicate decreased exponentially as a function of the amount of [gamma]- irradiation; the ability to induce SV 40 and adenovirus 7 T antigen decreased at a much slower rate. Nevertheless, the virus was still able to transform African green monkey kidney cells at a radiation dosage that had completely destroyed its replication ability. All transformed colonies were positive for SV40 T antigen but were negative for adenovirus 7 T antigen. The adenovirus 7-SV 40 hybrid transformed cells were superinfectible with SV40 virus. Two of the 3 transformed cell populations apparently did not sensitize hamsters against the appearance of Sv40 primary tumors, thus suggesting a deficiency in the SV40 transplantation antigen.


PMID: 4316019

Other references

Sobolevskii V.I., 1985: Vestibular resistance and change in blood circulation in orthostatic position in hyperthermia. Physiological effects and mechanisms of vestibular and orthostatic resistance were studied in 58 healthy men, aged 19-36. Their sublingual and skin temperature, ECG and moisture losses were determined. The active orthostatic test and the evaluatio...

Maqueo, M.T.; Calderon, J.J.; Guerra, A.Z., 1979: Salpingitis associated with the presence of nonmedicated IUDs. The histology of the Fallopian tubes in asymptomatic women using an IUD for at least 1 year was studied, using asymptomatic postpartum women and normally menstruating women scheduled for Pomeroy sterilization as controls. 225 patients, 75 with ine...

Laville, E., 1984: Banana tree cercosporioses and their treatment. Development and outlook. Fruits 39(3): 160-162

Koerner, S.; Pinsker, K.; Torres, M.; Colon, I.; Hagstrom, J.; Crane, R.; Veith, F.J., 1976: Lobar bronchial anastomoses to improve bronchial healing in lung transplantation. Surgical Forum 27(62): 195-197

Liu, G.; Li, F.; Zhang, S.; Jiang, Y.; Ma, G.; Shang, H.; Liu, J.; Feng, R.; Zhang, L.; Liao, M.; Zhao, B.; Li, K., 2015: Analyzing large-scale samples confirms the association between the ABCA7 rs3764650 polymorphism and Alzheimer's disease susceptibility. Large-scale genome-wide association studies (GWAS) have revealed that the ABCA7 rs3764650 polymorphism (or its proxies, namely rs115550680, rs3752246, and rs4147929) is associated with Alzheimer's disease (AD) susceptibility in individuals of...

L.B.han, D.; Delannoy, J.; Levin, R.L., 1989: Temperature mapping with MR imaging of molecular diffusion: application to hyperthermia. Efficacy and safety considerations for hyperthermia (HT) cancer therapy require accurate temperature measurements throughout the heated volume. Noninvasive thermometry methods have been proposed, including magnetic resonance (MR) imaging based on...

Appleton, R.E.; Thornton, L., 1996: Double blind comparison of vigabatrin vs placebo in newly diagnosed and previously untreated infantile spasms. Epilepsia 37(SUPPL 5): 125

Cao, S.Y.; Huang, H.; Qiao, X.S.; Sun, S.X., 1989: Studies on the process of flower differentiation and the mode of increase in the number of nodes in apple buds. Observations were carried out on node formation in both reproductive and vegetative buds in the apple cultivars Ralls, Golden Delicious and Jonathan. An increase in the number of nodes was highly positively correlated with time. The node number in...

Stevenson, R.D., 2017: Timely Referrals--Our Ethical Obligations to Our Colleagues. Journal of the California Dental Association 44(10): 651-651

Kirk R.G.; Lee P., 1988: Simultaneous measurements of rapid anion influx and efflux using x ray microanalysis. FASEB Journal 2(5): ABSTRACT 5836