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Transplantation of the Brown-Pearce rabbit carcinoma to rats

, : Transplantation of the Brown-Pearce rabbit carcinoma to rats. Biulleten' Eksperimental'noi Biologii i Meditsiny 52: 1068-1071

Translated from Byull. Eksptl. Biol. i Med. 52(9) 94-97. 1961. By a method for transplanting rabbit Brown-Pearce tumors to rats, heterogenic tumors were obtained in rats. By the 16th-29th day after inocula-tion their weight was from 10 to 20 gm. Later on a slow resolution of the tumor occurred, lasting for 1.5-2 months and more; this enabled them to study dynamic changes of its biological and biochemical properties. The tumor was maintained in a number of generations of previously prepared rats, as well as by its transplantations from the prepared rats to the healthy ones. The tumor taken in the prepared rats constituted 70%. When transplanted to rabbits Brown-Pearce tumor developed in generations of rats retains its primary properties.


PMID: 14036541

DOI: 10.1007/bf00790938

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