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Uber Bicarbon-atausscheidung und Kohlensauresystem im Ham wahrend akuter Hypoxie


, : Uber Bicarbon-atausscheidung und Kohlensauresystem im Ham wahrend akuter Hypoxie. Pflugers Arch Ges Physiol 249(5): 452-469

With the usual methods, the influence of low atmospheric pressure (decompression chamber) on urinary bicarbonate excretion was investigated on 5 healthy young men. The bicarbonate excretion of fasting subjects varies at sea-level between 0.01 and 1.6 mmols/hr. After several hrs. at an altitude of 6000 m., the bicarbonate excretion increases to 5 to 6 mmols/hr. Volitional hyperventilation at sea-level can raise the excretion up to 15 mmols/hr. At high altitude and during hyperventilation at sea-level, the normal relation between urinary pH and bicarbonate concn. is altered, and for the same pH less bicarbonate is found. This is due to a relative decrease in urinary CO2 tension.

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