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Uber die Rolle der Schadel-grundflache bei der Entstehung der genitalen Atrophie und der Fettsucht


, : Uber die Rolle der Schadel-grundflache bei der Entstehung der genitalen Atrophie und der Fettsucht. Virchows Arch Path Anat U Physiol 284(1): 49-66

Routine examinations at post mortem from a series ranging from suckling to old age established that: in southern Hungary the sagittal diameter of the sella turcica in infants is ca. 5 mm. and in adults 9.8-10.2; the height of the sella turcica in infants is ca. 3 mm., in adults 8.5-9.7. The form and shape of the sella turcica, also the size, form and direction of the clinoid processes, showed marked variability, as did the angle of the inferior surfaces of the midbrain with pituitary stalk and sella turcica and its various parts. [Such findings are illustrated in a series of dystrophy cases by 6 diagrams; some histologic evidences in these cases are also presented.] The author states that the anatomic departure from the normal of the cranial floor, especially sella turcica and the clinoid processes with exostosis, make for a damage to the mid-brain, the pituitary stalk and the pituitary itself; these aid in bringing about the symptom complex present in dystrophia adiposo-genitalis. The author adds a third division to the causes already recognized, and as the adiposity and genital atrophy following encephalitis are known as encephalogenous, and those arising from atrophy of the hypophysis are characterized as hypophyseal, he proposes to distinguish those due primarily to changes in form of the sella and clinoid process as osteogenous.

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