+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Localization of receptors and early events of phagocytosis in the macrophage

, : Localization of receptors and early events of phagocytosis in the macrophage. Experimental Cell Research 95(2): 365-375

We studied the attachment of MRBC, 1.1 m latex (foreign surface receptor), hemocyanin-DNP antiDNP Ab and sensitized SRBC (Fc receptor) to mouse peritoneal macrophages in culture, and the phagocytosis of 1.1 m latex, AbAg complex, and sensitized SRBC by macrophages. Both types of receptors appeared over the whole cell surface. The particles attached mostly in the central area of the cell, but peripheral attachment was also observed. Internalization of 1.1 m latex beads appeared to be mostly perinuclear, by sinking in of the cytoplasm with the attached particles, rather than a flow of membrane process over the beads. Also in the case of the AbAg complex attached to the Fc receptor internalization seemed mostly perinuclear and similar in mode to the latex ingestion. When attachment occurred in the periphery, active ruffling was observed. Sensitized SRBC internalization was seen mostly in the extreme periphery of the cells after the attached SRBC were moved from the perinuclear area where many of them first attached.


PMID: 1193157

DOI: 10.1016/0014-4827(75)90562-5

Other references

dos Santos, P.T.vares; de Abreu, K.C.istine Costa; das Fonseca, R.B.tista Medeiro; Vilela, C.G.tterres; Baptista Neto, J.A.tonio, 2008: Analise da microfauna de foraminiferos bentonicos e dados geoquimicos, ao longo de tres testemunhos na baia de Guanabara, Rio de Janeiro, Brasil. Anais do Congresso - Sociedade Brasileira de Geologia 44

Legg M.R.; Wong V., 1979: Faulting in the inner continental borderland offshore northern Baja California, Mexico. Abstracts with Programs - Geological Society of America 11(7): 464

Sandwith, N.Y., 1927: New species from the Andes of Argentina. Berberis comberi*(p. 175), a remarkable species with pentamerous flowers and no spine-leaves; Malvastrum corymbosum*(p. 176); Crist-aria eburnea (p. 178); Larrea simulans (p. 179); Anarthrophyllum ornithopodum (p. 179), with flowers congested in h...

Ichinose, H.; Wickstrom, J.K.; Hoerner, H.E.; Derbes, V.L., 1979: The early clinical presentation of synovial sarcoma. While synovial sarcoma most commonly presents as a painless mass, occasionally the cancer emerges in a misleading manner resulting in an unfavorable delay or error in diagnosis. A review of the litrature reveals 4 such occult patterns: pretumor ph...

Pouli, A.; Papadopoulos, A.; Papanastassiou, C.; Tsakanikas, S.; Stamatelou, M., 1999: Multiple myeloma as the presenting condition of HIV infection A case report. JAIDS Journal of Acquired Immune Deficiency Syndromes 21(1): A26, May 1

Hsieh, Y-Cheng.; Horng, T-Leng.; Lin, S-Fong.; Lin, T-Chao.; Ting, C-Tai.; Wu, T-Juey., 2008: d,l-Sotalol at therapeutic concentrations facilitates the occurrence of long-lasting non-stationary reentry during ventricular fibrillation in isolated rabbit hearts. The effects of d,l-sotalol at therapeutic concentrations (<or=10 mg/L) on wavefront dynamics during ventricular fibrillation (VF) and electrophysiological heterogeneity remain unclear. By using an optical mapping system, epicardial activation p...

Deng, Y-Jun.; Xia, J-Chuan.; Zhou, J.; Wang, Q-Jing.; Zhang, P-Yuan.; Zhang, L-Jun.; Rong, T-Hua., 2007: Antitumor efficacy of fusion cells from esophageal carcinoma cells and dendritic cells as a vaccine in vitro. Dendritic cells (DCs) are antigen-presenting cells, and DC-based fusion vaccine of DCs with tumor cells can induce specific immune response against tumor cells effectively. This study was to investigate the antitumor immunity efficacy of fusion va...

Clausen, C.P., 1932: The biology of Encyrtus infidis Rossi, a parasite of Lecanium kuncinsia Kuw. (Hymen.). Annals of the Entomological Society of America, 25: 670-687

Ergin, H.; Koklu, A.; Onar, B., 1988: Preparation of a goat pox vaccine in lambs kidney cell cultures and immunity tests in goats. An attenuated sheep pox virus was obtained by 64 passages in lamb kidney cell cultures. This strain (SP-B-LK 64), given by s.c. injection under the tail, to groups of 6 goats gave 100% immunity against challenge with a goat pox virus 3 or 6 months...

Lin, G.; Murphy, S.L.; Gaulton, G.N.; Hoxie, J.A., 2005: Modification of a viral envelope glycoprotein cell-cell fusion assay by utilizing plasmid encoded bacteriophage RNA polymerase. Many viruses enter cells via an interaction of the viral envelope glycoprotein (Env) with receptor inducing fusion of viral and cellular membranes. These interactions are often evaluated in cell-cell fusion, gene-reporting systems with effector ce...