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The comparative phase 2 trials to confirm the null hypothesis their importance especially in oncology

, : The comparative phase 2 trials to confirm the null hypothesis their importance especially in oncology. Biomedicine & Pharmacotherapy 37(2): 58-59


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Werner, B.; Scott, J.G.; Sottoriva, A.; Anderson, A.R.A.; Traulsen, A.; Altrock, P.M., 2016: The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories. Many tumors are hierarchically organized and driven by a subpopulation of tumor-initiating cells (TIC), or cancer stem cells. TICs are uniquely capable of recapitulating the tumor and are thought to be highly resistant to radio- and chemotherapy....

Sedick, Q.; Vaughan, J.; Pheeha, T.; Alli, N.A., 2015: Bone marrow aspirate microscopy v. bone marrow trephine biopsy microscopy for detection of Mycobacterium tuberculosis infection. Tuberculosis (TB) remains a global health problem. According to the 2013 Global Report on Tuberculosis, 8.6 million people developed TB in 2012 and 1.3 million died from the disease. An estimated 13% of people who developed TB in 2012 were HIV-pos...

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