+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Truncal vagotomy as a possible potentiator of gastric atony

, : Truncal vagotomy as a possible potentiator of gastric atony. American Journal of Surgery 155(2): 199-205

To stimulate ulcer patients undergoing operation for gastric outlet stenosis, pyloric obstruction was created in dogs and repaired with pyloroplasty to which was added truncal vagotomy, proximal gastric vagotomy, or no vagotomy. Gastric antral contractile activity after feeding a solid meal was studied before and after repair (2 week period of study). This activity was correlated with the initial lag and regulated phases of solid meal emptying. Five quantified indices of contractile activity measured during the first postprandial hour indicated variable and inconclusive results in the antrum during the lag phase (first 20 minutes). Consistent percentage changes in these indices after obstruction repair were seen during the subsequent regulated phase. Gastric work was reduced 28 to 35 percent, but not work capability (mean area), by pyloric obstruction in the no vagotomy dogs. Reductions seen in proximal gastric vagotomy dogs were not different from those in the no vagotomy dogs. Higher percentages of reduction in amplitude (70 percent) and mean area of contractions (53 percent) occurred after truncal vagotomy compared with what occurred in the no vagotomy dogs. Mean area was also reduced more compared with what occurred in the proximal gastric vagotomy dogs. These data indicate that the reduced gastric work after feeding and impaired work capability caused by truncal vagotomy when superimposed on that produced by pyloric obstruction may exaggerate gastric atony and contribute to the delayed recovery of gastric emptying seen in the clinical setting.


PMID: 3341543

DOI: 10.1016/s0002-9610(88)80693-7

Other references

Romero, C.; Heredia, R.; Pineda, J.; Serrano, J.A.; Mendoza, Gán.D.; Trápala, P.; Cordero, A.M., 2016: Efficacy of fluralaner in 17 dogs with sarcoptic mange. There are few licensed options for the treatment of canine sarcoptic mange. To evaluate the efficacy of fluralaner in dogs with sarcoptic mange infestation. Seventeen dogs with a diagnosis of Sarcoptes scabiei based on positive skin scrapings. A s...

Bali, H.S.; Singh, S.; Singh, D.P., 1984: Trial of some molluscicides on snails Melanoides tuberculatus and Vivipara bengalensis in laboratory. Frescon (WI8008), sodium pentachlorophenate, bayluscide and copper sulphate were highly effective in the control of Melanoides tuberculatus and Vivipara bengalensis. The results are tabulated.

de Rautlin de la Roy, Y.; Toma, V.; Bobin, B., 1978: In vitro activity of oxolinic acid and nalidixic acid against common urinary pathogens: a comparative study. A study was carried out to compare the sensitivity of 500 bacterial strains, isolated from patients with urinary tract infections, to oxolinic acid and nalidixic acid. The results showed that whilst both antibacterial agents were similar in their...

Lim, Y-beom.; Mays, C.E.; Kim, Y.; Titlow, W.B.; Ryou, C., 2010: The inhibition of prions through blocking prion conversion by permanently charged branched polyamines of low cytotoxicity. Branched polyamines are effective in inhibiting prions in a cationic surface charge density dependent manner. However, toxicity associated with branched polyamines, in general, often hampers the successful application of the compounds to treat pri...

McAllister, M.W.; Hsi, R.S.; Torrey, R.R.; Simmons, Z.; Baldwin, B.D.; Baldwin, D.Duane., 2011: In vitro comparison of changes in effective patient weight between purely laparoscopic and hand-assisted laparoscopic surgery. Subclinical rhabdomyolysis (RM) has been reported to occur at a high frequency in patients who are undergoing hand-assisted laparoscopic (HAL) surgery. Compressive forces of the surgeon's hand pushing the patient down onto the operating table...

Bielefeldt, K., 2014: From ischochymia to gastroparesis: proposed mechanisms and preferred management of dyspepsia over the centuries. Dyspeptic symptoms are common with most patients suffering functional disorders that remain a therapeutic challenge for medical practitioners. Within the last three decades, gastric infection, altered motility, and hypersensitivity have gained and...

Phillips, P.H., 1950: Relation of nutrition to good teeth. Good nutriton contributes to the formation of sound teeth during all stages of tooth development and good dietary habits can contribute toward reducing the oral organisms which are considered to be responsible for decay after the teeth have formed...

Holzel, A.; Komrower, G.M.; Wilson, V.K., 1952: Amino-aciduria in galactosaemia. British Medical Journal 1(4751): 194-195

Shiozawa, T.; Hahn, E.G., 2011: Archive of the Medical Education periodical. Gms Zeitschrift für Medizinische Ausbildung 28(2): Doc32-Doc32

Young R.C.; Canellos G.P.; Chabner B.A.; Schein P.S.; Brereton H.D.; Devita V.T., 1974: Treatment of malignant melanoma with methyl 1 2 chloroethyl 3 4 methylcyclohexyl 1 nitroso urea. Clinical Pharmacology & Therapeutics 15(6): 617-622