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A new method for the analysis of blood and plasma coagulation


, : A new method for the analysis of blood and plasma coagulation. Biomedical Sciences Instrumentation 29: 95-102

A new method of measuring and analyzing the clinically significant structural characteristics of blood clots is described, using an oscillatory flow instrument (Vilastic-3 Viscoelasticity Analyzer). The development of the viscous and elastic properties of the clot are monitored continuously at known levels of stress and strain in a cylindrical tube [1], and specific transitional events and their timing are obtained. In clinical practice, two types of clot analysis currently are in use. One measures the time required for the clot to reach some instrument-determined degree of development, which provides no information about the mechanical character of the clot. The second yields a continuous depiction of the way the forming clot affects the instrument [2] and gives numerical values that are inseparable from instrument characteristics. For greater universality, it is preferable to obtain the clot properties per se, as opposed to integrated clot-instrument parameters, and to document the timing of well-defined viscoelastic events. Measurements on clotting blood and plasma show that the dependence of clotting characteristics on measurements conditions and hence the need for precise control of stress or strain during the process.

US$29.90

PMID: 8329642


Other references

Tarel, M.R., 1935: Capture dun Squale bleu Squalus glaucus Linne, de ses deux Pilotes Scomber duclor L et dun Poisson volant Exocoetus volilans Bloch dans le Bassin dArcachon. Proces-Verbaux de la Societe Linneenne de Bordeaux, 862: 113-114

Burshtein L.M. (Burshteyn L.M), 2004: Possible control of size distribution of oil and gas fields. A new model simulates the size distribution of oil and gas fields in natural systems as a function of accumulation and dissipation rates described by equations with random parameters. The obtained model size distributions for large and largest oil...

Prisco, M.R.; Ochoa, J.A.; Yardimci, A.M., 2014: Predictions of vacuum loss of evacuated vials from initial air leak rates. Container closure integrity is a critical factor for maintaining product sterility and stability. Therefore, closure systems (found in vials, syringes, and cartridges) are designed to provide a seal between rubber stoppers and glass containers. To...

Ludden, C.T.; Scriabine, A.; Ulm, E.H.; Morgan, G.; Fisher, M.H.; Ruyle, W.V., 1979: Antihypertensive activity of some novel pyridinylidene arylurea derivatives in spontaneously hypertensive rats. 3 novel pyridinylidene arylurea derivatives were found to lower arterial pressure in spontaneously hypertensive rats. Their relative oral potency ranged from 6 to 32 times that of guanethidine. The onset of antihypertensive action following their...

Pilch, D., S.; Kirolos, M., A.; Liu, X.; Plum, G.E.ic; Breslauer, K., J., 1995: Berenil (1,3-bis(4'-amidinophenyl)triazene) binding to DNA duplexes and to a RNA duplex: Evidence for both intercalative and minor groove binding properties. Berenil is an antitrypanosomal agent that binds to nucleic acid duplexes. The generally accepted mode of berenil binding is via complexation into the minor groove of AT-rich domains of DNA double helices. We find that berenil can bind to RNA as we...

Buse, D.C.; Lipton, R.B., 2014: Global perspectives on the burden of episodic and chronic migraine. Cephalalgia 33(11): 885-890

Schedl, K.E., 1963: Zur Frage des Scolytus tiburtinus Klaus. 212. Beitrag zur Morphologie und Systematik der Scolytoidea. Entomologische Blaetter Krefeld, 59: 45

L.Pera, F., 1966: "Limited" functional impressions. Revista de la Asociacion Odontologica Argentina 54(8): 295-299

Srikrishna, A.; Reedy, T.J.gadeeswar, 1998: Stereoselective total synthesis of -tochuinyl acetate and -dihydrotochuinyl acetates. Details of the first total synthesis of the marine natural product dihydrotochuinyl acetate is described. Cyclopentenone annulation of p-methylacetophenone via a Claisen rearrangement-Wacker oxidation based sequence generated the cyclopentenone 3,...

McCarthy, L.K.; Molloy, E.J.; Twomey, A.R.; Murphy, J.F.A.; O'Donnell, C.P.F., 2013: A randomized trial of exothermic mattresses for preterm newborns in polyethylene bags. Wrapping very preterm newborns in polyethylene bags in the delivery room reduces hypothermia on admission to the NICU, but many infants remain cold despite their use. Placing polyethylene-wrapped infants on exothermic mattresses may reduce hypothe...