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A phytochemical and pharmacological study of Solanum villosum Chapter I


, : A phytochemical and pharmacological study of Solanum villosum Chapter I. Jour Amer Pharm Assoc 27(3): 217-224

Stem, root, leaves, and fruit were studied separately as to ash, extractives with petrol ether, ether, chloroform, and alcohol, and moisture and volatile constituents. The following specific constituents were studied: tannins, fixed oil, carbo-hydrates (starch, reducing and non-reducing sugars, pen-tosans), and inorganic salts. The toxic principle is believed due to a sapo-toxin or a compound similar to solanine. The plant is toxic in rather large doses, as death followed a few hours after administration of doses equivalent to 400 g. of fresh material per kg. body weight of rabbit used. Death followed respiratory failure.

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