+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Age-specific death rates of mice exposed to ionizing radiation and radiomimetic agents

, : Age-specific death rates of mice exposed to ionizing radiation and radiomimetic agents. R J C Harris, Editor Cellular Basis and Aetiology of Late Somatic Effects of Ionizing Radiation A Symposium 1962 p 285-297

The age-specific death rate increases irregularly with age, tending to rise exponentially with time beyond a certain age. Radiation and radiomimetic chemicals administered early in life increase the over-all age-specific death rate in a manner suggestive of ageing. When the age-specific death rates for individual diseases are analysed, the curves vary in shape and slope, and the effects of radiation appear quantitatively, if not qualitatively, variable. Age-specific death rates from radiogenic leukaemias (thymic lymphoma and myeloid leukaemia) appear unusual in that mortality from these diseases becomes maximal relatively early. . Analysis of the age-specific death rates for various other diseases, including non-neoplastic lesions, indicates that the life-shortening effects of radiation are not confined to induction of neoplasia or any other specific type of pathological change. Instead, they appear to be correlated with a general advancement in the age distribution of diseases otherwise associated with senescence. The results emphasize the complexity of the relation between the incidence of a disease and the radiation dose, owing to effects of radiation on intercurrent diseases affecting the survival of the population at risk.


Other references

Anonymous, 1983: Program for evaluating Chinese breeds crossed with European breeds. Bulletin Institut technique du porc 6(5): 7-8

Meyers, E.; Smith, D.A., 1964: Bioautography Of Antibiotic Spread-Layer Chromatograms. Journal of Chromatography 13: 129-132

Reitter, E., 1887: Insecta in itinere cl. N. Przewalskii in Asia centrali novissime lecta. vi. Clavicornia, Lamellicornia, et Serricornia. Horae Entomologicae Rossicae, XXI 201-234

Song, D.; Xiao, W.; Han, C.; Tian, Z., 2013: Geochronological and geochemical study of gneiss–schist complexes and associated granitoids, Beishan Orogen, southern Altaids. The tectonic nature of metamorphic terranes and their role in orogenesis are problematic. Here we present new U Pb ages and geochemical data for widespread metamorphic rocks and associated granitoids from Northwest China. Orthogneisses from the me...

Masinde, P.S., 2000: Ceropegia ahmarensis (Asclepiadaceae - Stapelieae), a new species from Somalia. A new species from north-western Somalia, Ceropegia ahmarensis Masinde (Asclepiadaceae - Stapelieae) probably allied to C. stenantha K. Schum., is described and illustrated. It is characterised by a climbing, succulent, glabrous stem; narrowly-ova...

Altman R.F.A.; Pugachia O.; Ballini Kerr I.; Pinto L.S., 1968: The influence of sub cutaneously injected phospho lipids and cholesterol on the formation and growth of tumors induced by 3 methyl cholanthrene. Archiv fuer Geschwulstforschung 31(2): 133-143

Zimmer, Carl, 2001: 'Inconceivable' bugs eat methane on the ocean floor. In this issue, a methane-devouring microbe is described by Orphan and colleagues. There are more than 10 trillion tons of this very potent greenhouse gas buried in the ocean floor, which could cause havoc with the world's climate if it were t...

Steele, R.J.C.; Kostourou, I.; McClements, P.; Watling, C.; Libby, G.; Weller, D.; Brewster, D.H.; Black, R.; Carey, F.A.; Fraser, C., 2010: Effect of gender, age and deprivation on key performance indicators in a FOBT-based colorectal screening programme. To assess the effect of gender, age and deprivation on key performance indicators in a colorectal cancer screening programme. Between March 2000 and May 2006 a demonstration pilot of biennial guaiac faecal occult blood test (gFOBT) colorectal scre...

Livingston, C.W.; Hardy, W.T., 1957: Vaccination of suckling lambs with blue-tongue vaccine. A satisfactory immunity against bluetongue was not produced by inoculating unweaned lambs with a commercial vaccine which had previously been shown to be satisfactory in older animals. Lambs should not be vaccinated for bluetongue until a period o...

Thomas, J.M.; Pfaff, W.W., 1976: Acute anuria secondary to renal artery stenosis. Three patients with acute onset of anuria secondary to renal malperfusion were successfully treated by revascularization. Twelve such patients have previously been reported. The role of surgery for prophylaxis in stenosing renal artery disease is...