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Alkylthioalkylation of nucleoside hydroxyl functions and its synthetic applications a new versatile method in nucleoside chemistry


, : Alkylthioalkylation of nucleoside hydroxyl functions and its synthetic applications a new versatile method in nucleoside chemistry. Tetrahedron Letters 32(51): 7593-7596

Treatment of appropriately protected nucleosides with a mixture of acetic acid, acetic anhydride and dialkylsulfoxide was shown to give O-(1-alkylthioalkylated) nucleosides that were oxidized to the corresponding sulfoxides and sulfones, or converted via O-halogenomethyl derivatives to various O-substituted nucleosides.

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Other references

Gadziev, G.K., 1962: The effect of exercise on the growth and development of pigs.. 24 piglings from 6 litters were divided into 3 groups and kept in styes without exercise (controls), in styes with free access to a yard, and in styes with free access to a yard+exercise over 1 0.5-2 km. daily In the 2 experimental groups the pigs...

Beck, Y.; Coetzee, J.N., 1980: Mobilization of the Proteus morganii chromosome by R plasmids. R plasmids R702, R711b, R1, D, Rip69, R447b, R471 and R394, belonging to different incompatibility groups, mobilized the Proteus morganii 2815 chromosome. Matings employing plasmids R711b or R702 as sex factors with doubly auxotrophic recipients p...

Rose, Anthony H., 1965: Chemical microbiology. This concise coverage of chemical microbiology includes discussion of the chemical activities of algae, bacteria, fungi, protozoa and yeasts. The volume will interest undergraduate and graduate students and others familiar with microbiology and bi...

Maher, E.A., 1989: Analyses of pectate lyases produced by Erwinia carotovora as a basis for determining their roles in pathogenesis. Aerobic potato tubers are resistant to maceration by E. carotovora, while maceration occurs in anaerobic tissues when E. carotovora populations reach 104 cfu. Attempts were made to determine whether resistance to maceration is due to polymerizatio...

Kerkez, S.A.; Poston, L.; Wolfe, C.D.; Quartero, H.W.; Carabelli, P.; Petruckevitch, A.; Hilton, P.J., 1990: A longitudinal study of maternal digoxin-like immunoreactive substances in normotensive pregnancy and pregnancy-induced hypertension. The serum of women in the third trimester of pregnancy demonstrates cross-reactivity with some commercially available antibodies to digoxin. A number of studies have suggested that levels of this digoxin-like immunoreactive substance(s) are furthe...

Friedlaender M.H.; Haghighi B.; Stein P.C.; Abelson M.B., 1991: A human model of conjunctival epithelial healing. Investigative Ophthalmology & Visual Science 32(4): 1160

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Al-Sarheed, Maha, 2004: Occupational exposures and hepatitis B vaccination statues in dental students in Central Saudi Arabia. Objective: To assess the nature of occupational exposures occurring to students and to assess the rate of reporting of incidents. Methods: A self-administrated questionnaire was circulated to third, fourth and final year undergraduate dental stude...

Mathews, W.; Mccutchan, J.A.; Shapiro, M.F.; Bozzette, S.A., 1999: National estimates of HIV-related symptoms. JGIM 14(SUPPL 2): 53, April

Endo, K.I.; Kawasaki, S.; Kinoshita, S., 2002: An IGG FC Binding Protein in Human Corneal Epithelium. Purpose: Rabbit IgG has a binding behavior toward human corneal epithelium that, in rabbit IgG used as negative control, has been a cause of trouble in corneal immunohistochemistry. This study was carried out in order to elucidate the binding mech...