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CD6-ligand interactions: a paradigm for SRCR domain function?


, : CD6-ligand interactions: a paradigm for SRCR domain function?. Immunology Today 18(10): 498-504

The scavenger receptor cysteine-rich (SRCR) superfamily, which includes proteins expressed by leukocytes, can be subdivided into groups A and B. Group B contains the lymphocyte cell-surface receptor CD6. This article reviews recent progress in understanding the interaction between CD6 and its ligand, activated leukocyte cell adhesion molecule (ALCAM). Analysis of the CD6-ALCAM interaction may help to understand how other SRCR domains bind to their ligands.

US$19.90

PMID: 9357143

DOI: 10.1016/s0167-5699(97)01130-4


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