geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Carbamazepine hepatotoxicity: another cause of the vanishing bile duct syndrome


, : Carbamazepine hepatotoxicity: another cause of the vanishing bile duct syndrome. Gastroenterology 102(4 Pt 1): 1385-1388

Serious carbamazepine hepatotoxicity is being recognized more frequently and is usually manifest as an acute granulomatous hepatitis that is self-limiting if the drug is withdrawn. The case of a 59-year-old man who developed the vanishing bile duct syndrome after 2 months of treatment with carbamazepine for glossopharyngeal neuralgia is reported. The characteristic histological features of this syndrome may also be seen in primary biliary cirrhosis, primary sclerosing cholangitis, graft-vs.-host disease after allogeneic bone marrow transplantation, chronic liver allograft rejection, and other drug reactions. The progress of this patient to date suggests that irreversible liver injury resulting in chronic liver disease is likely, in keeping with the clinical course of the vanishing bile duct syndrome in most cases.

US$19.90

PMID: 1551543

DOI: 10.1016/0016-5085(92)90780-3


Other references

Rosanova, Mía.Teresa.; Stamboulian, D.; Lede, R., 2012: Systematic review: which topical agent is more efficacious in the prevention of infections in burn patients?. Topical agents are widely used in the care of burn patients; however the efficacy to prevent local infections and/or sepsis has not been clearly established in studies with a high level of evidence. This systematic review was conducted to assess t...

Dihlmann, W.; Hering, L.; Bargon, G.W., 1988: The acquired hyperostosis syndrome. 2. In the second part of this publication, we describe some additional findings in cases of sternocostoclavicular hyperostosis. These include focal hyperostosis of the spine, in the pelvis and in the extremities and psoriatic skin lesions and severe...

Degerman, E.; Nyberg, P.; Sers, B., 2001: Havsoringens ekologi. The present report is a literature survey supplemented with data from SERS (Swedish Electrofishing RegiSter). The ecology of anadromous trout is described from hatching to spawning. Special emphasis is put on the three critical periods; the first...

Wegbreit, J.; Reisen, W.K., 2000: Relationships among weather, mosquito abundance, and encephalitis virus activity in California: Kern County 1990-98. The summer abundance of Culex tarsalis in Kern County, California, USA, during 1990-98 was related quantitatively to rainfall, snow depth and water content, and runoff of the Kern River. Total monthly rain that fell during winter, lagged by 4-6 mo...

Hallböök, T., 1999: With the body fluids balanced, vision would come back. Lakartidningen 96(20): 2503-2503

Freedman, D.S.; Brown, J.P.; Weir, D.G.; Scott, J.M., 1973: The reproducibility and use of the tritiated folic acid urinary excretion test as a measure of folate absorption in clinical practice: effect of methotrexate on absorption of folic acid. Subjects were given a loading dose of 15 mg folic acid (Folvite, Lederle) by intramuscular injection and 24 h later folic acid-3H was given by mouth, followed by another injection of 15 mg. In 26 control subjects from 30 to 57, on average 45.4% of...

Purnell, B.A., 2017: Ancestral legacy effects. Science 356(6335): 280-281

Jahn R.; Maycox P.R., 1988: Protein components and neurotransmitter uptake in brain synaptic vesicles. Thorn, N A , M Treiman And O H Petersen (Ed ) Proceedings Of The Alfred Benzon Symposium, 25 Molecular Mechanisms in Secretion; Symposium, Copenhagen, Denmark, June 21-25, 1987 668p Munksgaard International Publishers, Ltd : Copenhagen, Denmark Illus 411-424

Mantilla, C.B.; Yimam, Y.; Zhan, W.Z.; Prakash, Y.S.; Sieck, G.C., 1999: Alterations in neurotrophin receptor expression in rat diaphragm neuromuscular junctions following spinal cord hemisection. Society for Neuroscience Abstracts 25(1-2): 511

Tryphonopoulos, P.; Tzakis, A.G.; Kato, T.; Nishida, S.; Levi, D.; Nery, J.R.; Defaria, W.; Madariaga, J.J.; Weppler, D.; Mittal, N.; Thompson, J.F.; Ruiz, P., 2003: Abdominal evisceration, ex vivo resection and intestinal autotransplantation for the treatment of pathologic lesions of the root of the mesentery. BACKGROUND: Resection of lesions of the root of the mesentery is difficult because of their proximity to the blood supply of the intestine. Damage of its vessels necessitates resection of the otherwise intact intestine leading the patient to short...