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Comparison of frequencies of suicidal tendencies among patients receiving fluoxetine, lofepramine, mianserin, or trazodone

, : Comparison of frequencies of suicidal tendencies among patients receiving fluoxetine, lofepramine, mianserin, or trazodone. PharmacoTherapy 12(6): 451-454

To evaluate whether fluoxetine causes an important increased risk of suicidal behavior, we compared the frequency of attempted suicide, suicidal ideation, and aggressive behavior in persons who received fluoxetine, lofepramine, mianserin, and trazodone, based on information available on general practitioners' computers provided by Value Added Medical Products, Ltd. The frequency of these events was higher in fluoxetine users in the year prior to first treatment than in users of the other three antidepressants. The frequency of these events in the 90 days after the study drug was started was similar for the users of all four drugs. These data indicate that fluoxetine does not directly cause suicidal behavior at a substantially higher frequency than do lofepramine, mianserin, and trazodone.


PMID: 1492009

Other references

Mohd Ali; Siddiqui, N.A., 2000: Volatile oil constituents of Artemisia annua leaves. Analysis of the isolate by GLC and GC-MS resulted in isolation of 59 constituents in which 36 components comprising 73.1% of the total volatiles were identified. Quantitatively, the volatile oil was characterized by high amount of 15 monoterpenes...

Flandroy, L.; Galand, P., 1977: Oestrogen-induced changes in uterine cGMP: effects in vitro of oestradiol-17 beta [proceedings. Archives Internationales de Physiologie et de Biochimie 85(5): 975-977

Moran, G.R., 2016: The catalytic function of renalase: A decade of phantoms. Ten years after the initial identification of human renalase the first genuinely catalytic substrates have been identified. Throughout the prior decade a consensus belief that renalase is produced predominantly by the kidney and catalytically oxid...

Anderson, G.F.; Barnhart, M.I., 1962: The hepatic intracellular site of prothrombin production and storage. Abstract. It seems likely that prothrombin is synthesized in the endoplasmic reticulum (microsomes) and ultimately transported to the soluble compartment of the cell for storage and release.

Kostrikova, E.V., 1989: Experimental study of wound-healing effect of the preparation "Aekol" (artificial sea buckthorn oil). The author presents the data of her own experimental studies devoted to the investigation of specific wound-healing effect of the new medicinal preparation "Aekol". The author proves that like its prototype, native, sea-buckthorn oil, ae...

Yaginuma T.; Ushizima M., 1991: Proteolytic activity in the fat body during the pupal adult metamorphosis of the silkworm bombyx mori. Proteolytic activity with an optimum pH of 4.0 was found in fat bodies of 5 to 6 day-old female pupae of the silkworm, Bombyx mori, using azocolla as a synthetic substrate. The activity was strongly inhibited by p-chloromercuric benzoate at 0.5 mM...

Miescher, G., 1943: Skin eruptions and fever after sulfathiazole. Two different forms of skin eruptions may appear after admn. of sulfathiazole (Cibazol). I. Erythema nodosum-like exanthems of which 1/3 appears between the 2d and 3d day of treatment (2.5-12 gr. sulfathiazole) . The erythema may disappear in spit...

Anonymous, 1996: Position of the pediatric work community for children and teenager sports on the health aspects of boxing in childhood. Deutsche Zeitschrift fuer Sportmedizin 47(7-8): 442

Gurel, H.; Dogru, T., 2016: Betatrophin in nonalcoholic fatty liver disease. European Journal of Gastroenterology & Hepatology 28(4): 487-488

Reuter, E., 1905: Eine schadliche, neue Uropoda-Art. Acta Societatis pro Fauna et Flora Fennica, 27 1-17